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| PURPURIN Basic information |
Product Name: | PURPURIN | Synonyms: | CI NO 58205;CI 58205;1,2,4-TRIHYDROXY-9,10-ANTHRACENEDIONE;1,2,4-TRIHYDROXYANTHRAQUINONE;ALIZARIN PURPURIN;1,2,4-trihydroxyanthracene-9,10-dione;PURPURIN, FOR THE DETECTION OF B, PB;PURPURIN | CAS: | 81-54-9 | MF: | C14H8O5 | MW: | 256.21 | EINECS: | 201-359-8 | Product Categories: | Anthraquinones, Hydroquinones and Quinones;Anthraquinones;Hydroxyanthraquinones;Intermediates of Dyes and Pigments | Mol File: | 81-54-9.mol | |
| PURPURIN Chemical Properties |
Melting point | 253-256 °C(lit.) | Boiling point | 359.45°C (rough estimate) | density | 1.659 | refractive index | 1.4825 (estimate) | Fp | 113 °C | storage temp. | Inert atmosphere,Room Temperature | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | pka | 7.05±0.20(Predicted) | Colour Index | 58205 | form | Powder | color | Brown-red to brown | Water Solubility | 6.405mg/L(25 ºC) | Merck | 14,7945 | BRN | 1887127 | LogP | 4.600 (est) | CAS DataBase Reference | 81-54-9 | EPA Substance Registry System | Purpurin (81-54-9) |
| PURPURIN Usage And Synthesis |
Chemical Properties | brown-red to brown powder | Uses | Purpurin is an anthraquinone derivative and is well known as a colour pigment derived from madder plants. Purpurin was extensively utilized in herbal remedies, in food colouring and dyes for cotton pr
inting. Due to the high antioxidant activity exhibited by anthraquinone compounds, purpurin was determined through studies to possess potential radical scavenging effects. Purprin has also been shown
to have inhibitory effects towards serine protease. | Uses | A xanthine oxidase inhibitor. | Uses | xanthin oxidase inhibitor, irritant | Uses | Purpurin is a naturally occurring reddish-yellow pigment found in madder root (R. tinctorum) that has been used both in herbal remedies and as food coloring. It can also by synthetically derived from 9,10-anthraquinone. Purpurin is protective against a number of food-derived heterocyclic amines in bacterial mutagenicity assays through its inhibition of CYP450-dependent N-hydroxylation and reduction of N-hydroxylamines. Purpurine can also inhibit (IC50 = 6.6 μM) spermidine-induced autoactivation of plasma hyaluronan-binding protein, a serine protease that can activate coagulation factor VII and prourokinase. | Definition | ChEBI: A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4. | Purification Methods | Crystallise purpurin from aqueous EtOH, dry it at 100o. [Beilstein 8 IV 3568.] |
| PURPURIN Preparation Products And Raw materials |
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