2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide

2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Basic information
Product Name:2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide
Synonyms:2-[4-aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide;(2-[4-AMINOSULPHONYL-PHENYL]-ETHYL)-5-METHYLPYRAZINECARBOXAMIDE;N-{2-[4-(Aminosulfonyl)-phenyl]-ethyl}-5 Methylpyrazinecarboxamide;Glipizide Impurity Ⅰ:4-[2-(5-Methylpyrazinyl-2-carboxaMido)ethyl]benzenesulfonaMide;5-methyl-3-[2-(4-sulfamoylphenyl)ethyl]-2-pyrazinecarboxamide;4-[b-(5-Methylpyrazine-2-Carboxamido)Ethyl]-Benzensulphonamide;4-(b-(5-Methylpyrazine-2-carboxy-amido)ethyl)benzene Sulfonamide;4-{2-(5-METHYLPYRAZINE-2-CARBOXAMIDO)ETHYL}BENZENESULFLONAMIDE]
CAS:33288-71-0
MF:C14H16N4O3S
MW:320.37
EINECS:608-855-7
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Heterocycles;Sulfur & Selenium Compounds
Mol File:33288-71-0.mol
2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Structure
2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Chemical Properties
Melting point 237-239°C
density 1.41g/cm3 at 20℃
vapor pressure 0-0Pa at 20-25℃
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form neat
color Off-White to Light Beige
LogP0.2 at 19.8℃ and pH7
Surface tension72mN/m at 1g/L and 20℃
CAS DataBase Reference33288-71-0(CAS DataBase Reference)
Safety Information
HS Code 2935909550
MSDS Information
2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Usage And Synthesis
Chemical PropertiesOff-White Crystalline Solid
Uses4-[β-(5-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide (Glipizide EP Impurity A) is an intermediate in the synthesis of Glipizide (G410225).
2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Preparation Products And Raw materials
Ethanesulfonyl chloride 3-Aminobenzenesulfonamide 2-[4-Aminosulfonyl-phenyl]-ethyl-5-methylpyrazinecarboxamide Ethanol N,N-Dimethylformamide PHENYL RESIN Ethyl formate N-Acetylsulfanilyl chloride Ethylparaben Sulfanilamide PHENYL VALERATE ISOXADIFEN-ETHYL Ethyl acetate Ethyl acrylate Glipizide ETHYL 4-(B-(5-METHYLPYRAZINE-2-CARBOXYAMIDO)ETHYL)BENZENE SULFONAMIDE CARBAMATE Phenylacetic acid Formamide

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