2-AMINO-5-BENZOYL-BENZIMIDAZOLE

2-AMINO-5-BENZOYL-BENZIMIDAZOLE Basic information
Product Name:2-AMINO-5-BENZOYL-BENZIMIDAZOLE
Synonyms:2-AMINO-5-BENZOYL-BENZIMIDAZOLE;2-AMino-5(6)-benzoylbenziMidazole;(2-AMino-1H-benziMidazol-6-yl)phenylMethanone;G 1029;R 18986;Mebendazole IMpurity A;(2-aMino-1H-benzo[d]iMidazol-5-yl)(phenyl)Methanone;Mebendazole Related CoMpound A
CAS:52329-60-9
MF:C14H11N3O
MW:237.26
EINECS:
Product Categories:Metabolites & Impurities;Amines;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:Mol File
2-AMINO-5-BENZOYL-BENZIMIDAZOLE Structure
2-AMINO-5-BENZOYL-BENZIMIDAZOLE Chemical Properties
Melting point 176-185°C
Boiling point 379.79°C (rough estimate)
density 1.1513 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka10.59±0.10(Predicted)
form neat
color White to Light Beige
BRN 3550536
Stability:Hygroscopic
CAS DataBase Reference52329-60-9
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
RTECS OB1085000
MSDS Information
2-AMINO-5-BENZOYL-BENZIMIDAZOLE Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesThe minor urinary metabolite of Mebendazole (M200500) in man. Mebendazole impurity.
Uses2-AMINO-5-BENZOYL-BENZIMIDAZOLE is a novel heterocyclic NF-κB inhibitor used in pharmaceutical compositions.
DefinitionChEBI: 2-Amino-5-benzoylbenzimidazole is a member of benzophenones.
Safety ProfileAcute poison by intraperitoneal route. Moderately toxic by ingestion. An experimental teratogen. See also KETONES. A flammable liquid. When heated to decomposition it emits very toxic fumes of NOx,.
2-AMINO-5-BENZOYL-BENZIMIDAZOLE Preparation Products And Raw materials
Preparation Products2-AMino-5(6)-[α-hydroxybenzyl]benziMidazole
Mebendazole tablets

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