ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Other amino acid derivatives 3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&

3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& Basic information
Product Name:3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&
Synonyms:3,3μ,5-Triiodo-L-thyronine hydrate sodium salt;3,3',5-Triiodo-L-thyronine sodium salt hydrate 95%;Sodium(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoatehydrate(1:1:1);3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& USP/EP/BP;Liothyronine sodium hydrate
CAS:345957-19-9
MF:C15H11I3NO4Na
MW:672.96
EINECS:
Product Categories:Peptide Synthesis;Phenylalanine Derivatives;Unnatural Amino Acid Derivatives
Mol File:345957-19-9.mol
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& Structure
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& Chemical Properties
Melting point 205 °C (dec.)(lit.)
storage temp. Store at -20°C
solubility DMF: 0.25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 1 mg/ml
form A crystalline solid
optical activity[α]22/D +21.5°, c = 2 in 1 N HCl: ethanol, 1:2
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& Usage And Synthesis
Description3,3'',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5''-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling. It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 μM.
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& Preparation Products And Raw materials
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