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| | 2,3-Dichloro-5-(trichloromethyl)pyridine Basic information |
| | 2,3-Dichloro-5-(trichloromethyl)pyridine Chemical Properties |
| Boiling point | 278-279 °C(lit.) | | density | 1.636 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.5900(lit.) | | Fp | 150 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | -3.03±0.10(Predicted) | | EPA Substance Registry System | 2,3-Dichloro-5-(trichloromethyl)pyridine (69045-83-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2933399990 |
| | 2,3-Dichloro-5-(trichloromethyl)pyridine Usage And Synthesis |
| Uses | 2,3-dichloro-5-(trifluoromethyl)pyridine (DCTF) is an important organic intermediate for the agrochemical industry in particular for use in the synthesis of fluazinam and fluopicolide as well as other pesticidal active pyridine compounds. | | Synthesis | Conversion of Nicotinic acid to 2,3-dichloro-5-(trichloromethyl)pyridine. Nicotinic acid (2 g, 16.25 mmole) and phosphorous pentachloride (27 g, 130 mmole) was mixed in a 50 ml Teflon autoclave. The autoclave was closed and heated in a 180 °C warm metal block. After 48 hours was the autoclave cooled to 25 °C and opened. The resulting suspension was quenched in a mixture of NaOH (10 %) and dichlorom ethane under stirring, keeping the temperature below 30 °C. The phases were separated and the organic phase was evaporated to dryness to get the crude product. The product was hereafter distilled and 2,8 g of 2,3-dichloro-5-(trichloromethyl)pyridine was obtained (65% yield). |
| | 2,3-Dichloro-5-(trichloromethyl)pyridine Preparation Products And Raw materials |
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