4-Amino-3-nitrophenol

4-Amino-3-nitrophenol Basic information

Product Name:	4-Amino-3-nitrophenol
Synonyms:	2-amino-5-hydroxynitrobenzene;4-Amino-3-Nitrophenol98%;Phenol, 4-amino-3-nitro-;3-NITRO-4-AMINOPHONOL;4-Amino-3-nitrophenol,4-Hydroxy-2-nitroaniline;2-Nitro-4-hydroxyaniline;4-Aminophenol-3-nitrophenol;4-AMino-3-nitrophenol, 98% 25GR
CAS:	610-81-1
MF:	C6H6N2O3
MW:	154.12
EINECS:	210-236-8
Product Categories:	Amines;Aromatics;Intermediates & Fine Chemicals;Mutagenesis Research Chemicals;Pharmaceuticals;Aromatic Phenols;Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles
Mol File:	610-81-1.mol

4-Amino-3-nitrophenol Chemical Properties

Melting point	150-154 °C(lit.)
Boiling point	322.46°C (rough estimate)
density	1.3617 (estimate)
refractive index	1.6890 (rough estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Crystalline Powder
pka	9.21±0.10(Predicted)
color	deep violet
Water Solubility	soluble
BRN	2210196
Stability:	Hygroscopic
LogP	1.320 (est)
CAS DataBase Reference	610-81-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-36-37/39
RIDADR	2811
WGK Germany	3
PackingGroup	III
HS Code	29222900

MSDS Information

Provider	Language
4-Hydroxy-2-nitroaniline	English
SigmaAldrich	English
ACROS	English
ALFA	English

4-Amino-3-nitrophenol Usage And Synthesis

Chemical Properties	Dark red powder
Uses	4-Amino-3-nitrophenol is an aminonitrophenol isomer used in hair dyes, potent human skin sensitizers and other cosmetic products with very low levels of mutagenic activity.
Uses	4-Amino-3-nitrophenol was used in the synthesis of benzimidazole based Factor Xa (trypsin-like serine protease) inhibitors and 4-(4-amino-3-nitrophenoxy)phthalonitrile. It was also employed as matrix during visible matrix-assisted laser desorption/ionization mass spectrometry.
Contact allergens	This hair dye used for semipermanent colors seems to be a rare sensitizer.

4-Amino-3-nitrophenol Preparation Products And Raw materials

Raw materials	2-nitrophenyl azide-->Benzoic acid 4-(acetylamino)phenyl ester-->Benzamide, N-[4-(benzoyloxy)phenyl]--->4-Acetoxyacetanilide-->3-NITRO-4-ACETAMIDOPHENOL-->Sulfuric acid-->4-Acetoxy-1-acetylamino-2-nitro-benzene-->2-Nitroaniline-->Acetaminophen-->Acetanilide
Preparation Products	4-Amino-2-nitrophenol-->tert-butyl 4-hydroxy-2-nitrophenylcarbaMate-->4-IODO-3-NITROPHENOL-->4-Chloro-3-nitrophenol-->RAF265(CHIR-265)-->3-Nitro-4-(1H-pyrrol-1-yl)benzenol

Nitroaniline N,N-BIS(2-HYDROXYETHYL)-2-AMINO-5-NITROPHENOL Iron, complexes with diazotized 2-amino-5-nitrobenzenesulfonic acid coupled with diazotized 2-amino-4-nitrophenol and resorcinol AURORA 6742 3-Amino-4-nitrophenol 2-AMINO-4-NITROPHENOL-6-SULFONAMIDE 4-NITROPHENOL 4-ETHOXY-2-NITROANILINE 4-BENZYLOXY-2-NITROANILINE ALTRENOGEST Azoic Diazo Component 1 2,5-DINITROPHENOL N,O-Di(2-hydroxyethyl)-2-amino-5-nitrophenol,N,O-di(hydroxyethyl)-2-amino-5-nitrophenol Sodium picramate AMINO ACIDS 6-Chloro-2-(N-Ethyl)Amino-4-Nitrophenol CHLOROPHOSPHONAZO III 2-[bis(2-hydroxyethyl)amino]-5-nitrophenol

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