FERULIC ACID METHYL ESTER

FERULIC ACID METHYL ESTER Basic information
Product Name:FERULIC ACID METHYL ESTER
Synonyms:FERULIC ACID METHYL ESTER (METHYL FERULATE);(SYNONYMS: METHYL FERULATE);Methyl Ferulate [4-Hydroxy-3-MethoxycinnaMic Acid Methyl Ester];METHYL 4-HYDROXY-3-METHOXYCINNAMATE;METHYL FERULATE;METHYL TRANS-3-(4'-HYDROXY-3'-METHOXYPHENYL)-ACRYLATE;METHYL 3-(4-HYDROXY-3-METHOXY)CINNAMATE;FERULIC ACID METHYL ESTER
CAS:2309-07-1
MF:C11H12O4
MW:208.21
EINECS:1308068-626-2
Product Categories:Aromatic Esters
Mol File:2309-07-1.mol
FERULIC ACID METHYL ESTER Structure
FERULIC ACID METHYL ESTER Chemical Properties
Melting point 62-65°C
Boiling point 163 °C(Press: 1 Torr)
density 1.204±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Sparingly)
form Solid
pka8.88±0.18(Predicted)
color White to Off-White
Water Solubility Slightly soluble in water.
LogP2.209 (est)
CAS DataBase Reference2309-07-1(CAS DataBase Reference)
NIST Chemistry Reference2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, methyl ester(2309-07-1)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
RTECS GD9470000
HS Code 2918999090
MSDS Information
ProviderLanguage
ALFA English
FERULIC ACID METHYL ESTER Usage And Synthesis
UsesFerulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid methyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 74.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). Ferulic acid methyl ester, at 10-25 μg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages.
UsesFerulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.
DefinitionChEBI: A cinnamate ester that is the methyl ester of ferulic acid. It has been isolated from Pisonia aculeata.
FERULIC ACID METHYL ESTER Preparation Products And Raw materials
Preparation Products2-(4-fluorophenyl)-8,8-dimethyl-7,8-dihydroimidazo[1,2-a]pyrazin-6(5H)-one
Ferulic Acid Sodium ferulic METHYL CAFFEATE Levobupivacaine hydrochloride Tylosin tartrate Methyldopa (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Hydroxychloroquine sulfate 2-Ethylhexyl ferulate Ceftiofur hydrochloride Caffeic acid 3,4-Dihydroxyphenylethanol Arbutin Resveratrol Quinocetone Ethyl 4'-hydroxy-3'-methoxycinnamate Methyl cinnamate 3-Methoxycinnamic acid Methyl Ferulate

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