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| | 3,4',5-TRIMETHOXY-TRANS-STILBENE Basic information |
| Product Name: | 3,4',5-TRIMETHOXY-TRANS-STILBENE | | Synonyms: | 3,4',5-TRIMETHOXY-TRANS-STILBENE;(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene;(E)-3,4',5-Trimethoxystilbene;3,5,4'-Trimethoxy-trans-stilbene;Trimethoxystilbene;3,4,5-TRIMETHOXY-TRANS-STILBENE 95+%;TRANS-1-(3,5-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHYLENE;TRISMETHOXY RESVERATROL | | CAS: | 22255-22-7 | | MF: | C17H18O3 | | MW: | 270.32 | | EINECS: | 694-659-7 | | Product Categories: | Resveratrol;Intermediates & Fine Chemicals;Stilbenes;Pharmaceuticals | | Mol File: | 22255-22-7.mol |  |
| | 3,4',5-TRIMETHOXY-TRANS-STILBENE Chemical Properties |
| Melting point | 57°C | | Boiling point | 423.8±35.0 °C(Predicted) | | density | 1.104±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO: ≥34mg/mL | | form | powder to crystal | | color | white to tan | | CAS DataBase Reference | 22255-22-7 |
| | 3,4',5-TRIMETHOXY-TRANS-STILBENE Usage And Synthesis |
| Description | trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM. | | Chemical Properties | Pale Yellow Oil | | Uses | A resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization | | Uses | A resveratrol analog with a variety of pharmacology action, including
inst microtubule-destabilization | | Uses | Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced. |
| | 3,4',5-TRIMETHOXY-TRANS-STILBENE Preparation Products And Raw materials |
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