2-Amino-5-bromopyrazine

2-Amino-5-bromopyrazine Basic information

Product Name:	2-Amino-5-bromopyrazine
Synonyms:	5-BROMOPYRAZINAMINE;5-BROMOPYRAZIN-2-AMINE;5-BROMO-PYRAZIN-2-YLAMINE;5-BROMO-2-PYRAZINAMINE;BUTTPARK 29\02-91;2-aimo-5-bromopyrazine;5-Bromo-2-aminopyrazine;2-AMINO-5-BROMOPYRAZINE: TECH.
CAS:	59489-71-3
MF:	C4H4BrN3
MW:	174
EINECS:	626-202-4
Product Categories:	amine\| alkyl bromide;Chloropyrazines, etc.;Bases & Related Reagents;Nucleotides;Pyrazines, Pyrimidines & Pyridazines;Building Blocks;Halides;Pyrazines, Pyrimidines & Pyridazines;Pyrazine;Nucleotides and Nucleosides;Pyrazines;Halogenated Heterocycles;Heterocyclic Building Blocks;PyrazinesHeterocyclic Building Blocks;Amines and Anilines;Heterocycles;pharmacetical;Amines;Aromatics;Building Blocks/Intermediates
Mol File:	59489-71-3.mol

2-Amino-5-bromopyrazine Chemical Properties

Melting point	113-117 °C (lit.)
Boiling point	274.2±35.0 °C(Predicted)
density	1.844±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Ethanol, Ethyl Acetate, Methanol
pka	1.66±0.10(Predicted)
form	Brown Needles
color	Light yellow to Brown
InChIKey	KRRTXVSBTPCDOS-UHFFFAOYSA-N
CAS DataBase Reference	59489-71-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/38-43-44-36/37/38-20/21/22
Safety Statements	26-37/39-45-36/37/39-22-36/
WGK Germany	3
Hazard Note	Irritant
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English

2-Amino-5-bromopyrazine Usage And Synthesis

Chemical Properties	Brown Needles
Uses	Used without prior protection of the amino group in a palladium-catalyzed cross-coupling with pyridylboronic acids leading to pyrazinylpyridines.

2-Amino-5-bromopyrazine Preparation Products And Raw materials

Raw materials	Dichloromethane-->Sodium carbonate-->Magnesium sulfate-->N-Bromosuccinimide-->Aminopyrazine-->2-Amino-3,5-dibromopyrazine-->2-Amino-3-bromopyrazine-->3-Amino-6-bromopyrazine-2-carboxylic acid
Preparation Products	2,5-Dibromopyrazine-->2-BROMO-5-METHOXYPYRAZINE-->Cyclobutanecarbonitrile, 1-[6-(5-amino-2-pyrazinyl)-3-pyridinyl]--->5-(3-THIENYL)-2-PYRAZINAMINE-->6-AMINOPYRAZINE-2-BORONIC ACID PINACOL ESTER-->PyrazinaMine, 5-(4-chlorophenyl)-->5-(4-methoxyphenyl)pyrazin-2-amine

2-Amino-5-bromopyrazine METHYL 3-AMINO-6-BROMOPYRAZINE-2-CARBOXYLATE,3-Amino-6-bromopyrazine-2-carboxylic acid methyl ester 3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE,3-AMINO-6-BROMOPYRAZINE-2-CARBONITRILE, 95+% Aminopyrazine ALTRENOGEST 5-BROMO-3-(2-PHENYL-PYRROLIDIN-1-YL)-PYRAZIN-2-YLAMINE 6-Aminocaproic acid 2-Bromopyrazine Glycine Pyrazinamide Bromine Tris(hydroxymethyl)aminomethane Sulfachoropyrazine sodium AMINO ACIDS 6'-BROMO-3-PHENYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL-3'-YLAMINE 3-Aminophenol Glipizide Mestinon

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