(S)-(-)-4-Amino-2-hydroxybutyric acid

(S)-(-)-4-Amino-2-hydroxybutyric acid Basic information
Product Name:(S)-(-)-4-Amino-2-hydroxybutyric acid
Synonyms:L-(-)-ALPHA-HYDROXY-GAMMA-AMINOBUTYRIC ACID;(S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID;(S)-4-AMINO-2-HYDROXYBUTYRIC ACID;L-(-)-alpha-hydroxy-γ-amino butyric acid(HABA);(R)-(-)-4-Amino-2-hydroxybutyricacid;(S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID, 9 6%;(S)-(-)-AMINO-2-HYDROXYBUTYRIC ACID;L-(-)-α-Hydroxy-γ-AminoButyricAcid
CAS:40371-51-5
MF:C4H9NO3
MW:119.12
EINECS:
Product Categories:Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks;chiral;API intermediates
Mol File:40371-51-5.mol
(S)-(-)-4-Amino-2-hydroxybutyric acid Structure
(S)-(-)-4-Amino-2-hydroxybutyric acid Chemical Properties
Melting point 200-203 °C (lit.)
alpha -30 º (c=1, water)
Boiling point 222.38°C (rough estimate)
density 1.3126 (rough estimate)
refractive index -30 ° (C=1, H2O)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Methanol (Very Slightly, Heated), Water
form Crystalline Powder, Crystals and/or Chunks
pka3.47±0.10(Predicted)
color White to beige
optical activity[α]23/D 30°, c = 1 in H2O
Water Solubility almost transparency
Sensitive Hygroscopic
Stability:Hygroscopic
InChIKeyIVUOMFWNDGNLBJ-VKHMYHEASA-N
CAS DataBase Reference40371-51-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26
WGK Germany 3
HS Code 29225090
MSDS Information
ProviderLanguage
ACROS English
(S)-(-)-4-Amino-2-hydroxybutyric acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses(S)-(-)-4-Amino-2-hydroxybutyric acid may be used in the preparation of 6′-amino-1-N-[(S)-4-amino-2-hydroxybutyryl]-6′-deoxylividomycin A.
Uses(S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.
General Description(S)-(-)-4-Amino-2-hydroxybutyric acid is an important moiety of butirosin, an aminoglycoside antibiotic.
(S)-(-)-4-Amino-2-hydroxybutyric acid Preparation Products And Raw materials
D-2-AMINO-4-HYDROXYBUTYRIC ACID,D-Homoserine, (R)-2-Amino-4-hydroxybutyric acid,(R)-2-AMINO-4-HYDROXYBUTYRIC ACID (2S,3R)-2-Amino-3-hydroxybutyric acid methyl ester (2R,3S)-3-Amino-2-hydroxybutyric acid (2S,3R)-2-[[(2S)-2-(Benzyloxycarbonylamino)-4-pentenoyl]amino]-3-hydroxybutyric acid methyl ester (2R,3S)-2-[[[5-(Dimethylamino)-1-naphtyl]sulfonyl]amino]-3-hydroxybutyric acid 2-Hydroxy-4-amino butanoic acid DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE (R)-4-N-BOC-AMINO-2-HYDROXYBUTYRIC ACID (+/-)-4-AMINO-3-HYDROXYBUTYRIC ACID,4-AMINO-3-HYDROXYBUTYRIC ACID (2R,3S)-2-Amino-3-hydroxybutyric acid ethyl ester (R)-(-)-AMINO-3-HYDROXYBUTANOIC ACID 3-Amino-2-hydroxybutyric acid D-4-Amino-3-hydroxybutyric acid 2-(1-ethyl-2,3-dioxopiperazine-4-carbox amido)-3-hydroxybutanoic acid DL-2-AMINO-3-HYDROXYBUTYRIC ACID (S)-N-CARBOBENZYLOXY-4-AMINO-2-HYDROXYBUTYRIC ACID 96%,(S)-N-CBZ-4-AMINO-2-HYDROXYBUTYRIC ACID g-Amino-b-hydroxybutyric acid Amikacin EP Impurity F

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