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| | 5(S)-HETE-D8 Basic information |
| Product Name: | 5(S)-HETE-D8 | | Synonyms: | 5(S)-HETE-D8;5S-HYDROXY-6E,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID;(S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid | | CAS: | 330796-62-8 | | MF: | C20H24D8O3 | | MW: | 328.52 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 5(S)-HETE-D8 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml |
| | 5(S)-HETE-D8 Usage And Synthesis |
| Uses | 5(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 5(S)-HETE by GC- or LC-mass spectrometry (MS). 5(S)-HETE is produced by the action of 5-lipoxygenase on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to the 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4. |
| | 5(S)-HETE-D8 Preparation Products And Raw materials |
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