| | 3,5-Dimethylphenol Chemical Properties |
| Melting point | 61-64 °C(lit.) | | Boiling point | 222 °C(lit.) | | density | 1.115 | | vapor pressure | 5-5.4Pa at 25℃ | | refractive index | 1.5146 (estimate) | | Fp | 109 °C | | storage temp. | room temp | | form | Crystalline Solid | | pka | pK1:10.15 (25°C) | | color | White to orange | | Water Solubility | 5.3 g/L (25 ºC) | | Sensitive | Air & Light Sensitive | | Merck | 14,10082 | | BRN | 774117 | | Exposure limits | ACGIH: TWA 1 ppm | | InChIKey | TUAMRELNJMMDMT-UHFFFAOYSA-N | | LogP | 2.35 at 25.5℃ | | CAS DataBase Reference | 108-68-9(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 3,5-dimethyl-(108-68-9) | | EPA Substance Registry System | 3,5-Dimethylphenol (108-68-9) |
| | 3,5-Dimethylphenol Usage And Synthesis |
| Description | 3,5-Dimethylphenol was used in simultaneous determination of urinary concentrations of phenol, o-, p-, m-cresols, 1-, 2-naphthol and xylenol isomers by capillary gas chromatography. It was used as starting reagent for total synthesis of landomycin A, most potent antitumor angucycline antibiotic and optically active polypropionate units. It also finds application as adhesives, sealant chemicals, plating and surface treating agents. It is also used as a solvent for cleaning or degreasing. Further, it is employed as a chemical intermediate for antioxidants, phenolic resins, active pharmaceutical ingredients and metaxalone (muscle relaxant).
| | Chemical Properties | 3,5-Xylenol is a crystalline solid. | | Uses | 3,5-Dimethylphenol finds application as adhesives, sealant chemicals, plating and surface treating agents. It is also used as a solvent for cleaning or degreasing. Further, it is employed as a chemical intermediate for antioxidants, phenolic resins, active pharmaceutical ingredients and metaxalone (muscle relaxant). | | Definition | ChEBI: A member of the class of phenols that phenol substituted by methyl groups at positions 3 and 5. | | General Description | Colorless to off-white crystalline solid. Odor threshold 1 ppm. Taste threshold 0.001 mg/L. | | Air & Water Reactions | 3,5-Dimethylphenol is hygroscopic. Insoluble in water. | | Reactivity Profile | 3,5-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides, and oxidizing agents. 3,5-Dimethylphenol corrodes steel, brass, copper, and copper alloys. | | Fire Hazard | Flash point data for 3,5-Dimethylphenol are not available. 3,5-Dimethylphenol is probably combustible. | | Safety Profile | Poison by
intraperitoneal route. Moderately toxic by
ingestion. A severe eye irritant. Questionable
carcinogen with experimental tumorigenic
data. When heated to decomposition it
emits acrid smoke and irritating fumes. See
also other xylenol entries. | | Potential Exposure | 3,5-Xylenol is used as an antioxidant,
solvent, plasticizer, wetting agent; and in pharmaceuticals.
Xylenols are also used in pesticides, fuel, and lubricant
additives; as a rubber chemical; in dyestuff manufacture.
There are actually six xylenol isomers. | | Shipping | UN 2261 Xylenols, Hazard Class: 6.1; Labels:
6.1-Poisonous materials. | | Purification Methods | Purify it as for 3,4-dimethylphenol. [Beilstein 6 IV 3141.] | | Incompatibilities | A weak organic acid. Incompatible with
oxidizers (chlorates, nitrates, peroxides, permanganates,
perchlorates, chlorine, bromine, fluorine, etc.); contact may
cause fires or explosions. Keep away from alkaline materials,
strong bases, strong acids, oxoacids, and epoxides. | | Waste Disposal | Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator
equipped with an afterburner and scrubber. All federal, state,
and local environmental regulations must be observed. |
| | 3,5-Dimethylphenol Preparation Products And Raw materials |
| Raw materials | m-Xylene-->2,6-Dimethylphenol | | Preparation Products | 3,4-Dimethylphenol-->4-(Methylthio)-3,5-xylenol-->XMC-->N,N-Dimethylglycine-->4-Pyridinamine,5-ethyl-2-methyl-, 1-oxide-->4-Bromo-3,5-dimethylphenol-->2,6-Dimethyl-4-aminophenol-->CHLOROXYLENOL RELATED COMPOUND A (25 MG) (2- CHLORO-3,5-DIMETHYLPHENOL)-->4-Hydroxy-2,6-dimethylbenzoic acid-->2-Pyridylacetic acid-->2,6-DIMETHYLBENZOQUINONE-->3-Methyl-2-cyclohexen-1-one-->4-Chloro-3,5-dimethylphenol-->3-(3,5-DIMETHYLPHENOXY)-2-BUTANONE |
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