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| | Fluoroacetonitrile Basic information |
| | Fluoroacetonitrile Chemical Properties |
| Melting point | -13 °C | | Boiling point | 79-80 °C (lit.) | | density | 1.061 g/mL at 25 °C (lit.) | | refractive index | 1.333 | | Fp | 7°F | | Water Solubility | Slightly soluble in water | | form | clear liquid | | color | Colorless to Almost colorless | | CAS DataBase Reference | 503-20-8(CAS DataBase Reference) | | NIST Chemistry Reference | Fluoroacetonitrile(503-20-8) |
| | Fluoroacetonitrile Usage And Synthesis |
| Uses | Fluoroacetonitrile is a water disinfectant byproduct that showed weak inhibition of rat hepatic glutathione S-transferases in vitro. Fluoroacetonitrile is also a reagent in the preparation of the PAD4
inhibitor F-Amidine. | | Uses | Fluoroacetonitrile has been used in preparation of:
- 2-fluoromethyl-4,4,6-trimethyl-1,3-oxazine
- α-fluorinated acetophenone
- 2-amino-2-fluoromethyl-3-pentenenitrile, a key intermediate in the synthesis of 2,5-diamino-2-fluoromethyl-3(E)-pentenoic acid
| | Synthesis Reference(s) | Journal of Medicinal Chemistry, 26, p. 1551, 1983 DOI: 10.1021/jm00365a002 |
| | Fluoroacetonitrile Preparation Products And Raw materials |
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