3-Methylthiopropanol

3-Methylthiopropanol Basic information
Product Name:3-Methylthiopropanol
Synonyms:3-(Methylthio)propane-1-ol;3-Methionol;3-Methylthio-1-propanol>=98.0%;3-Methyl thiopropaol;Methionol 3-Hydroxypropyl Methyl Sulfide 3-Methylmercaptopropyl Alcohol 3-Methylthio-1-propanol;Methionol ,98%;3-(Methylthio)-1-propanol,Methionol;3-Methythio propanol
CAS:505-10-2
MF:C4H10OS
MW:106.19
EINECS:208-004-6
Product Categories:Intermediates;Sulfur & Selenium Compounds;Aliphatics;API intermediates;Various Intermediates;Aliphatic;sulfide Flavor;Sulfides flavors
Mol File:505-10-2.mol
3-Methylthiopropanol Structure
3-Methylthiopropanol Chemical Properties
Melting point -100°C (estimate)
Boiling point 89-90 °C13 mm Hg(lit.)
density 1.03 g/mL at 25 °C(lit.)
FEMA 3415 | 3-(METHYLTHIO)PROPANOL
refractive index n20/D 1.49(lit.)
Fp 195 °F
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka14.87±0.10(Predicted)
form liquid (estimate)
color Clear Colorless to Light Yellow
Specific Gravity1.03
Odorat 0.10 % in propylene glycol. sulfurous onion sweet soup vegetable
Odor Typemeaty
JECFA Number461
LogP0.40
CAS DataBase Reference505-10-2(CAS DataBase Reference)
NIST Chemistry Reference1-Propanol, 3-(methylthio)-(505-10-2)
EPA Substance Registry SystemMethionol (505-10-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-24/25-36/37/39
RIDADR UN 3334
WGK Germany 3
TSCA Yes
HS Code 29309090
MSDS Information
ProviderLanguage
Methionol English
SigmaAldrich English
ACROS English
ALFA English
3-Methylthiopropanol Usage And Synthesis
Description3-(Methylthio)propanol has a powerful sweet soup or meat-like odor and flavor in high dilution. May be prepared from propylene chlorhydrin and sodium hydrosulfide.
Chemical Properties3-(Methylthio)propanol has a powerful, sweet, soup or meat-like odor and flavor in high dilution.
Chemical PropertiesColorless Liquid
OccurrenceReported found in fermented soy sauce, tomatoes, grape wines, apple, melon, pineapple, asparagus, rye bread, cheeses, cured pork, beer, cognac, malt whiskey, cider, sherry, coffee, litchi, shrimp and apple brandy
Uses3-Methylthiopropanol is used in the meat essence composition.It is also used in meat, potato, and cheese flavorings.
Uses3-(Methylthio)-1-propanol is used in the meat essence composition.
PreparationFrom propylene chlorhydrin and sodium hydrosulfide
DefinitionChEBI: An alkyl sulfide that is propan-1-ol substituted by a methylsulfanyl group at position 3. It is a volatile compound found in wines and produced during fermentation.
Aroma threshold valuesDetection: 0.2 ppb. Aroma characteristics at 1.0%: sulfurous, savory, vegetative raw potato-like, fresh tomato, metallic anchovy-like with some onion and garlic nuances
Taste threshold valuesTaste characteristics at 0.5 ppm: metallic, tomato, potato, anchovy-like with savory brothy and malt-like nuances.
Synthesis Reference(s)Tetrahedron, 48, p. 5933, 1992 DOI: 10.1016/S0040-4020(01)90183-8
General Description3-(Methylthio)-1-propanol is a volatile sulfur flavor compound mainly found in wine and soy sauce.
3-Methylthiopropanol Preparation Products And Raw materials
Raw materialsOxygen-->Allyl alcohol-->METHYL MERCAPTAN
Preparation Products3-(Methylthio)propionaldehyde-->METHYL-(3-HYDROXYPROPYL) SULFONE
3-(Methylthio)propionaldehyde 3-Methylthiopropanol S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE 3-METHYLTHIO-1,2-PROPANEDIOL 5-THIO-D-GLUCOSE SINIGRIN H-D-CYS(BZL)-OH Borane-methyl sulfide complex CARBOXYMETHYLMERCAPTOSUCCINIC ACID 3,3'-Thiodipropionic acid S-Methyl-L-cysteine ISOMETHIOZIN Dimethyl sulfide Thioridazine 7-Aminocephalosporanic acid Isopropyl alcohol Methimazole 1-Propanol

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