L-GLUTAMIC-2,3,3,4,4-D5 ACID

L-GLUTAMIC-2,3,3,4,4-D5 ACID Basic information
Product Name:L-GLUTAMIC-2,3,3,4,4-D5 ACID
Synonyms:L-GLUTAMIC ACID (2,3,3,4,4-D5);L-GLUTAMIC-2,3,3,4,4-D5 ACID;L-GLUTAMIC ACID (2,3,3,4,4-D5, 97-98%);(2S)-2-AMinopentanedioic Acid-d5;(S)-(+)-GlutaMic Acid-d5;(S)-2-AMino-1,5-pentanedioic Acid-d5;(S)-2-AMinopentanedioic Acid-d5;1-AMinopropane-1,3-dicarboxylic Acid-d5
CAS:2784-50-1
MF:C5H4D5NO4
MW:152.16
EINECS:
Product Categories:Amino Acids & Derivatives, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals;Amino Acids;Amino AcidsStable Isotopes;G-H;Stable Isotopes;Alphabetical Listings;Amino Acids 13C, 2H, 15N
Mol File:2784-50-1.mol
L-GLUTAMIC-2,3,3,4,4-D5 ACID Structure
L-GLUTAMIC-2,3,3,4,4-D5 ACID Chemical Properties
Melting point 205 °C (dec.)(lit.)
storage temp. Refrigerator
solubility Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated)
form Solid
color White to Off-White
optical activity[α]25/D +31°, c = 2 in 5 M HCl
Water Solubility Water : 14.29 mg/mL (93.91 mM; ultrasonic and warming and heat to 60°C)
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
L-GLUTAMIC-2,3,3,4,4-D5 ACID Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
UsesL-Glutamic Acid-d5 is an non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
DefinitionChEBI: L-glutamic acid-d5 is a L-glutamic acid and a deuterated compound.
Biochem/physiol ActionsGlutamic acid (or glutamate) functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as gamma-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase. Appl- L-Glutamic acid-2,3,3,4,4-d5 has been used as an internal standard in metabolomics and lipidomics profiling.
L-GLUTAMIC-2,3,3,4,4-D5 ACID Preparation Products And Raw materials
Raw materials2-Ketoglutaric acid
4-Aminobutyric acid L-Tryptophan L-Lysine Sodium nitrite L-Cysteine L-GLUTAMIC-2,3,3,4,4-D5 ACID N-ACETYL-L-GLUTAMIC-2,3,3,4,4-D5 ACID N-Cbz-D-glutamic acid α-benzyl ester, Z-D-glutamic acid 1-benzyl ester D-GLUTAMIC-2,3,3,4,4-D5 ACID PEMETREXED-D5 L-Glutamic acid-15N,d9 N-ACETYL-D-GLUTAMIC-2,3,3,4,4-D5 ACID Boc-L-glutamic acid γ-cyclohexyl ester, Boc-L-glutamic acid 5-cyclohexyl ester L-Glutamic acid-13C5,15N,d9 DL-GLUTAMIC-2,3,3,4,4-D5 ACID

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