| | 3,3'-IMINODIPROPIONITRILE Basic information |
| Product Name: | 3,3'-IMINODIPROPIONITRILE | | Synonyms: | TIMTEC-BB SBB007920;.beta.,.beta.’-Iminodipropionitrile;2,2’-dicyano-diethylamin;2341 I.S.;2341i.s.;2-cyano-n-(2-cyanoethyl)-ethanamin;3-(2-Cyano-ethylamino)-propionitrile;3,3'-Iminodipropanenitrile | | CAS: | 111-94-4 | | MF: | C6H9N3 | | MW: | 123.16 | | EINECS: | 203-922-3 | | Product Categories: | Organics | | Mol File: | 111-94-4.mol |  |
| | 3,3'-IMINODIPROPIONITRILE Chemical Properties |
| Melting point | -6 °C | | Boiling point | 205 °C25 mm Hg(lit.) | | density | 1.02 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.47(lit.) | | Fp | >230 °F | | storage temp. | 2-8°C | | pka | 6.13±0.19(Predicted) | | form | clear liquid | | color | Colorless to Light yellow to Light orange | | Water Solubility | Soluble in water. | | Stability: | Stable, but moisture sensitive. Reaction with moisture may lead to a build up of pressure in sealed bottles. Combustible. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 111-94-4(CAS DataBase Reference) | | EPA Substance Registry System | 3,3'-Iminobispropanenitrile (111-94-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | RIDADR | UN 3334 | | WGK Germany | 2 | | RTECS | UG2975000 | | TSCA | Yes | | HS Code | 29269095 | | Hazardous Substances Data | 111-94-4(Hazardous Substances Data) | | Toxicity | A neurotoxic synthetic
nitrile that causes proximal axonopathies in the spinal cord and
brain stem. The proximal axonal swellings are due to interruption
of slow axonal transport, resulting in a large accumulation
of neurofilaments. Secondary to these effects is a progressive
atrophy of the distal axon, secondary demyelination, and gliosis.
The slow axonal transport defect appears to be selective,
as little evidence for perturbations in fast axonal transport have
been reported. Behaviorally, IDPN induces hyperactivity, a
“waltzing syndrome,” circling and head-rolling in mice and
rats. IDPN intoxication has been advanced as a model for
certain motor neuron degenerative diseases such as amyotropic
lateral sclerosis (ALS) and hereditary canine spinal muscular
atrophy (HCSMA). |
| | 3,3'-IMINODIPROPIONITRILE Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | Bis(2-cyanoethyl)amine is used as pharmaceutical intermediates. | | General Description | Clear colorless liquid. | | Air & Water Reactions | Water soluble. Moisture sensitive. Some 18-month old bottles of 3,3'-IMINODIPROPIONITRILE exploded, probably owing to slow hydrolysis and buildup of pressure. Solutions in water are unstable above pH 4. . | | Reactivity Profile | Nitriles, such as 3,3'-IMINODIPROPIONITRILE, may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids. | | Fire Hazard | 3,3'-IMINODIPROPIONITRILE is combustible. |
| | 3,3'-IMINODIPROPIONITRILE Preparation Products And Raw materials |
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