Adenosine-5'-diphosphate disodium salt

Adenosine-5'-diphosphate disodium salt Basic information
Product Name:Adenosine-5'-diphosphate disodium salt
Synonyms:5'-ADP-NA2;adenosine5’-(trihydrogendiphosphate),disodiumsalt;Adenosine-5'-diphosphata(ADP),disodium salt;Adenosine-5'-diphosphate disodiuM salt(ADPNa);Adenosine 5 -Diphosphate DisodiuM Salt ;5'-ADENYLDIPHOSPHORIC ACID, DISODIUM SALT;ADENOSINE DIPHOSPHATE DINA SALT;ADP DISODIUM
CAS:16178-48-6
MF:C10H15N5O10P2.2Na
MW:471.16
EINECS:240-314-7
Product Categories:Pharmaceutical Intermediates;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Nucleotides and their analogs;Nucleic acids;nucleoside;Pharmaceutical
Mol File:16178-48-6.mol
Adenosine-5'-diphosphate disodium salt Structure
Adenosine-5'-diphosphate disodium salt Chemical Properties
storage temp. -20°C
form Powder
color White
optical activity[α]20/D 29.6±1°, c = 0.5% in 0.5 M Na2HPO4
Water Solubility Soluble in water.
Sensitive Hygroscopic
BRN 3645656
InChIKeyAIZARHCNBKWDRW-KWIZKVQNSA-L
CAS DataBase Reference16178-48-6(CAS DataBase Reference)
EPA Substance Registry SystemAdenosine 5'-(trihydrogen diphosphate), disodium salt (16178-48-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
10-21
TSCA Yes
HS Code 29349990
MSDS Information
ProviderLanguage
5'-ADP-Na2 English
SigmaAldrich English
ALFA English
Adenosine-5'-diphosphate disodium salt Usage And Synthesis
DescriptionAdenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
Chemical PropertiesWhite crystalline powder
UsesAdenosine-5'-diphosphate disodium salt is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
ApplicationAdenosine-5'-diphosphate disodium salt is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels.
Biochem/physiol ActionsAdenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y1 and P2Y12. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.
Adenosine-5'-diphosphate disodium salt Preparation Products And Raw materials
Adenosine 3-ACETYLPYRIDINE TPN, SODIUM Adenosine-5'-diphosphate disodium salt Sodium Phosphate, Dibasic AP5A SODIUM SALT ADENOSINE 5'-TRIPHOSPHATE, TETRASODIUM SALT, [2,8-3H] ADENOSINE-5'-[GAMMA-(4-AMINOPHENYL)]TRIPHOSPHATE, SODIUM SALT ADPG DISODIUM SALT Diphosphate 3'-NADPH SODIUM SALT Ethylenediaminetetraacetic acid disodium salt ADENOSINE 5'-TRIPHOSPHATE, TETRASODIUM SALT, [8-14C]- 2-METHYLTHIOADENOSINE TRIPHOSPHATE TETRASODIUM Β-GLYCEROPHOSPHATE, DISODIUM SALT 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 2-(METHYLTHIO)-ADENOSINE 5'-TRIHYDROGEN DIPHOSPHATE TRISODIUM Pamidronate disodium salt ADENOSINE 5'-DIPHOSPHATE TRISODIUM SALT HYDRATE

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