6-Chloropurine riboside

6-Chloropurine riboside Basic information
Product Name:6-Chloropurine riboside
Synonyms:2-(6-chloropurin-9-yl)-5-hydroxyMethyltetrahydrofuran-3,4-diol;6-CLPR;6-CHLORO-9-BETA-D-RIBOFURANOSYL-9H-PURINE;6-CHLORO-9-(BETA-D-RIBOFURANOSYL)PURINE;6-CHLOROPURINE NUCLEOSIDE;6-CHLOROPURINE-9-BETA-D-RIBOFURANOSIDE;6-CHLOROPURINE-9-RIBOSIDE;6-CHLOROINOSINE
CAS:5399-87-1
MF:C10H11ClN4O4
MW:286.67
EINECS:226-438-4
Product Categories:Bases & Related Reagents;Nucleotides
Mol File:5399-87-1.mol
6-Chloropurine riboside Structure
6-Chloropurine riboside Chemical Properties
Melting point 158-162 °C (dec.) (lit.)
Boiling point 614.8±65.0 °C(Predicted)
density 2.03±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Sparingly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated,
pka13.06±0.70(Predicted)
form Powder
color White to slightly yellow
Water Solubility Soluble in water. (10.6 mg/mL)
BRN 40573
InChIKeyXHRJGHCQQPETRH-HMEJCUHCSA-N
CAS DataBase Reference5399-87-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
RTECS UO7520800
10-23
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
6-Chloropurine riboside Usage And Synthesis
Chemical PropertiesColourless Crystalline Powder
Uses6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
Uses6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. 6-Chloropurine riboside, especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.
UsesA substrate for adenosine deaminase
6-Chloropurine riboside Preparation Products And Raw materials
6-Chloropurine riboside 6-AMINO-2-CHLOROPURINE RIBOSIDE HEMIHYDRATE Ribavirin 2,6-Dichloropurine riboside 6-CHLOROPURINE RIBOSIDE-5''-MONOPHOSPHATE DISODIUM SALT 95% (HPLC) 6-Chloropurine 2-METHYLTHIO-6-CHLOROPURINE RIBOSIDE 95% (HPLC) NUCLEOSIDE PHOSPHORYLASE BACTERIAL 6-CHLOROPURINE RIBOSIDE-5'-O-MONOPHOSPHATE SODIUM SALT,6-CHLOROPURINE RIBOSIDE 5'-MONOPHOSPHATE DISODIUM SALT Difluorochloromethane 2-Chloroadenosine 6-Chloropurine riboside 3'',5''-cyclic monophosphoric acid sodium salt,6-CHLOROPURINE RIBOSIDE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Purine Inosine 6-Chloropurine ribonucleoside 6-CHLOROPURINE RIBOSIDE-5'-DIPHOSPHATE SODIUM SALT 6-Chloropurine Riboside Acetonide 6-Chloropurine Riboside for

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