| | 4-NITROBENZHYDRAZIDE Basic information | | Synthesis |
| | 4-NITROBENZHYDRAZIDE Chemical Properties |
| Melting point | 210-214 °C | | Boiling point | 292.97°C (rough estimate) | | density | 1.3539 (rough estimate) | | refractive index | 1.5860 (estimate) | | solubility | acetone: soluble0.5g/10 mL, clear, yellow | | pka | 2.77, 11.17(at 25℃) | | form | crystals | | color | Yellow | | PH Range | Colorless (8.2) to yellow (9.5) | | λmax | 267nm | | BRN | 519882 | | Major Application | corrosion inhibitor, disinfectant, cosmetics, paints toothpaste, mouthwash, antifungal agent, inhibit fibrosis, antituberculosis agent | | CAS DataBase Reference | 636-97-5(CAS DataBase Reference) | | EPA Substance Registry System | 4-Nitrobenzoylhydrazine (636-97-5) |
| | 4-NITROBENZHYDRAZIDE Usage And Synthesis |
| Synthesis | Dissolve 218 g of p-nitrobenzyl acetate in 500 ml of hot methanol, stir, and slowly add 380 g of 15% sodium hydroxide solution. After the addition was completed, it was placed for 5 minutes, and then poured into ice water to precipitate a precipitate. The filtered precipitate was decolorized with activated carbon in hot water, and recrystallized to give p-nitrobenzoicacidhydrazide 110-121 g . | | Chemical Properties | yellow crystalline powder | | Uses | 4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method. | | Definition | ChEBI: A C-nitro compound in which the nitro group is substituted into the 4-position of benzohydrazide. |
| | 4-NITROBENZHYDRAZIDE Preparation Products And Raw materials |
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