4,4'-DIMETHOXYBENZHYDROL

4,4'-DIMETHOXYBENZHYDROL Basic information
Product Name:4,4'-DIMETHOXYBENZHYDROL
Synonyms:Bis(4-methoxyphenyl) carbinol~4,4-Dimethoxydiphenylmethanol;p,p'-dimethoxybenzhydryl alcohol;4,4'-Dimethoxybenzhydrol, 98+%;(4,4'-Dimethoxybenzhydryl) alcohol;(4-Methoxyphenyl)(4-methoxyphenyl)methanol;4-Methoxy-α-(4-methoxyphenyl)benzenemethanol;α-(4-Methoxyphenyl)-4-methoxybenzenemethanol;BIS(4-METHOXYPHENYL)CARBINOL
CAS:728-87-0
MF:C15H16O3
MW:244.29
EINECS:211-975-9
Product Categories:Benzhydrols, Benzyl & Special Alcohols
Mol File:728-87-0.mol
4,4'-DIMETHOXYBENZHYDROL Structure
4,4'-DIMETHOXYBENZHYDROL Chemical Properties
Melting point 67-70 °C(lit.)
Boiling point 347.2°C (rough estimate)
density 1.1263 (rough estimate)
refractive index 1.5570 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility methanol: 0.1 g/mL, clear
pka13.68±0.20(Predicted)
form Solid
color White
Water Solubility Soluble in water (0.44 g/L @ 25°C), methanol (0.1 g/mL).
BRN 748532
CAS DataBase Reference728-87-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36/37-26
WGK Germany 3
HS Code 29094990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4,4'-DIMETHOXYBENZHYDROL Usage And Synthesis
Chemical Propertieswhite to off-white crystalline powder
Uses4,4?-Dimethoxybenzhydrol was used to study the kinetics and mechanism of oxidation of substituted benzhydrols to corresponding benzophenones in the presence of Hg(OAc)2 by N-bromosuccinimide. It is useful in the protection of glutamine and asparagine residues in peptide synthesis, reagent for the N-protection of amides.
General Description4,4′-Dimethoxybenzhydrol causes N-alkylation of amides, lactams, carbamates, ureas and anilines in acetic acid during H2SO4 catalysis.
4,4'-DIMETHOXYBENZHYDROL 5'-DMT-5-BROMO-DU PHOSPHORAMIDITE (CHIRAL) 5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 4,4',4''-TRIMETHOXYTRITYL ALCOHOL BCECF-AM Fluorescein diacetate DMT-2'O-Methyl-rU Phosphoramidite 5-CFDA N-succinimidyl ester 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 2',7'-DICHLOROFLUORESCIN DIACETATE N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 5(6)-CARBOXY-2',7'-DICHLOROFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite 5-CARBOXYFLUORESCEIN DIACETATE 5'-O-Dimethoxytrityl-deoxythymidine

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