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N-Boc-N'-trityl-L-histidine

N-Boc-N'-trityl-L-histidine Basic information
Product Name:N-Boc-N'-trityl-L-histidine
Synonyms:(S)-2-(tert-butoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propanoic acid;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoic acid;Nα-(tert-butyloxy)carbonyl-Nim-triphenylmethyl-L-histidine;Boc-L-His(Trt);N-Boc-His(Trt)-OH;(S)-2-(Boc-aMino)-3-(1-trityl-4-iMidazolyl)propionic acid, 95%;His(Trt)-OH;Boc-His(Trt)-OH >=98.0% (TLC)
CAS:32926-43-5
MF:C30H31N3O4
MW:497.58
EINECS:
Product Categories:Boc-Amino Acids and Derivative;Boc-Amino acid series
Mol File:32926-43-5.mol
N-Boc-N'-trityl-L-histidine Structure
N-Boc-N'-trityl-L-histidine Chemical Properties
Melting point ~130 °C (dec.)
alpha 12.5 º (C=1% IN MEOH)
Boiling point 667.5±55.0 °C(Predicted)
density 1.16±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Sparingly)
pka3.17±0.10(Predicted)
form Solid
color White to Off-White
optical activity[α]20/D +12.5±1.0°, c = 1% in methanol
BRN 732035
InChIKeyOYXZPXVCRAAKCM-SANMLTNESA-N
CAS DataBase Reference32926-43-5(CAS DataBase Reference)
Safety Information
WGK Germany 3
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
N-Boc-N'-trityl-L-histidine Usage And Synthesis
Chemical PropertiesWhite to off white powder
UsesBoc-His(Trt)-OH was used in the study to prepare and study structure-activity relationship of amino acid amides as selective inhibitors for dipeptidyl peptidases.
N-Boc-N'-trityl-L-histidine Preparation Products And Raw materials
Boc-Aib-OH N-Boc-N'-trityl-L-histidine N-Boc-L-Histidine 1-Isopropylimidazole 1-BENZHYDRYL-1H-IMIDAZOLE 1-(Triphenylmethyl)imidazole N-Carbobenzyloxyglycine Toluene (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Trityl candesartan cilexetil PENICILLIN V BOC-GLY-LEU-OH L-Histidine BOC-HIS(1-ME)-OH 1-Triphenylmethyl-4-methylimidazole p-Toluic acid Triphenylmethyl Chloride H-HIS(TRT)-OH
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