5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine

5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Basic information
Product Name:5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
Synonyms:5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine;Palbociclib-001;Palbociclib impurity 3/5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine;2-Pyrimidinamine, 5-bromo-4-chloro-N-cyclopentyl-;5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amineQ: What is 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Q: What is the CAS Number of 5-Bromo-4-chloro-N-cyclopentylpyrimidin-2-amine
CAS:1823404-28-9
MF:C9H11BrClN3
MW:276.56
EINECS:
Product Categories:
Mol File:1823404-28-9.mol
5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Structure
5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Chemical Properties
Boiling point 398.2±45.0 °C(Predicted)
density 1.643±0.06 g/cm3(Predicted)
pka1.87±0.10(Predicted)
Safety Information
MSDS Information
5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Usage And Synthesis
Uses5-?Bromo-?4-?chloro-?N-?cyclopentylpyrimidin?-?2-?amine is an impurity of Palbociclib (P139900), (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
5-bromo-4-chloro-N-cyclopentylpyrimidin-2-amine Preparation Products And Raw materials
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one PD 0332991 HCl 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2,3-d]pyriMidin-7(8H)-one Palbociclib-012 5-(piperazin-1-yl)pyridin-2-aMine 1-Piperazinecarboxylic acid, 4-(2-aMino-3-pyridinyl)-, 1,1-diMethylethyl ester tert-butyl 4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate Palbociclib-030 Phosphine oxide, tris (2-methylphenyl)- Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]- 8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one Palbociclib-029 4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate Palbociclib tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate Palbociclib-007 4-(3-NITRO-PYRIDIN-2-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

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