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| | 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Basic information |
| | 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties |
| Boiling point | 792.0±60.0 °C(Predicted) | | density | 1.363±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 10.74±0.40(Predicted) |
| | 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Usage And Synthesis |
| Description | Pomalidomide-PEG4-Ph-NH2 is comprised of the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. Pomalidomide-PEG4-Ph-NH2 is used in PROTAC technology as a E3 ligase ligand-linker conjugate that incorporates PEG technology that can be linked to a wide range of "warheads" that bind to proteins of interest. |
| | 4-((2-(2-(2-(2-(4-aminophenoxy)ethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Preparation Products And Raw materials |
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