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Erlotinib Impurity 20

Erlotinib Impurity 20 Basic information
Product Name:Erlotinib Impurity 20
Synonyms:2-amino-4,5-bis(2-methoxyethoxy)benzamide;Erlotinib Impurity R;Erlotinib impurity 17/2-amino-4,5-bis(2-methoxyethoxy)benzamide;2-amino-4,5-bis(3-methoxypropyl)-benzamide;6,7-bis(2-methoxyethoxy)quinazolin-4-amine;Erlotinib Hydrochloride iMpurity 12;Erlotinib Hydrochloride iMpurity 17;Erlotinib-13
CAS:236750-62-2
MF:C13H20N2O5
MW:284.31
EINECS:
Product Categories:
Mol File:236750-62-2.mol
Erlotinib Impurity 20 Structure
Erlotinib Impurity 20 Chemical Properties
Boiling point 408.3±45.0 °C(Predicted)
density 1.198±0.06 g/cm3(Predicted)
pka15.77±0.50(Predicted)
Safety Information
MSDS Information
Erlotinib Impurity 20 Usage And Synthesis
Uses2-Amino-4,5-bis(2-methoxyethoxy)benzamide is an impurity of Erlotinib (E625008), a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival.
Erlotinib Impurity 20 Preparation Products And Raw materials
Preparation ProductsErlotinib
Ethyl 3,4-dihydroxybenzoate 4-Quinazolinamine,N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride(1:1) Erlotinib Imp.15 Benzoic acid, 3,4-bis(2-methoxyethoxy)-, methyl ester OSI 413 DesMethyl Erlotinib Carboxylate Acid 4-CHLORO-7-(2-CHLORO-ETHOXY)-6-(2-METHOXY-ETHOXY)-QUINAZOLINE METHYL ESTER, 4,5-BIS(2-METHOXYETHOXY)-2-NITROBENZOIC ACID Erlotinib Hydrochloride iMpurity Erlotinib hydrochloride Erlotinib 2-ETHYNYLANILINE 98 DesMethyl Erlotinib Carboxylate Acid 7-O-DesMethoxy-7-O-chloroethyl Erlotinib Hydrochloride Erlotinib Impurity 22 Erlotinib Impurity 36 HCl 4-(3-AMINOPHENYL)-2-METHYL-3-BUTYN-2-OL Erlotinib
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