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Avibactam Impurity 15

Avibactam Impurity 15 Basic information
Product Name:Avibactam Impurity 15
Synonyms:Avibactam Impurity 26;(S,E)-ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate;(S,Z)-Ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate;2-Piperidinecarboxylic acid, 5-[(phenylmethoxy)imino]-, ethyl ester, (2S)-;ethyl (S,E)-5-((benzyloxy)imino)piperidine-2-carboxylate
CAS:1416134-60-5
MF:C15H20N2O3
MW:276.33
EINECS:
Product Categories:
Mol File:1416134-60-5.mol
Avibactam Impurity 15 Structure
Avibactam Impurity 15 Chemical Properties
Boiling point 401.6±55.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
pka6.66±0.40(Predicted)
Safety Information
MSDS Information
Avibactam Impurity 15 Usage And Synthesis
Uses(2S)-5-[(Phenylmethoxy)imino]-2-piperidinecarboxylic Acid Ethyl Ester is an impurity of Avibactam (A794850, Na Salt); a novel β-lactamase inhibitor with a non-lactam structural scaffold. Avibactam irreversibly inhibits lactamase from Mycobacterium tuberculosis.
Avibactam Impurity 15 Preparation Products And Raw materials
Preparation ProductsAvibactam INT 1-->AvibactaM
N-[[[2-(Aminooxy)ethyl]amino]sulfonyl]carbamic acid 1,1-dimethylethyl ester ethyl (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate (2S,5R)-ethyl 5-(benzyloxyaMino)piperidine-2-carboxylate tert-butyl ((2S)-1-(((2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)oxy)propan-2-yl)carbamate 4-[2-(Aminooxy)ethoxy]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester (2S,5R)-N'-acetyl-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide Avibactam Impurity 3(2R,5S) Carbamic acid, [2-(aminooxy)ethyl]-, 1,1-dimethylethyl ester (9CI) trans-6-benzyloxy-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylic acid (2S,5R)-6-(benzyloxy)-7-oxo-N'-picolinoyl-1,6-diazabicyclo[3.2.1]octane-2-carbohydrazide tert-butyl (2S)-2-((((2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)oxy)methyl)pyrrolidine-1-carboxylate tert-butyl (N-(2-(((2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)oxy)ethyl)sulfamoyl)carbamate Avibactam Impurity 10 tert-butyl (S)-2-((aminooxy)methyl)pyrrolidine-1-carboxylate methyl (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate Avibactam Sodium Isomer Avibactam Impurity 15 Avibactam Impurity 7
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