Mometasone

Mometasone Basic information
Product Name:Mometasone
Synonyms:icariins;Mometasone (Mometasone Furoate EP Impurity G);MOMETASONE;9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;MometasoneFuroateBase;Mometasone Furoate EP Impurity G/Mometasone;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-;Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI)
CAS:105102-22-5
MF:C22H28Cl2O4
MW:427.36
EINECS:818-819-4
Product Categories:
Mol File:105102-22-5.mol
Mometasone Structure
Mometasone Chemical Properties
Melting point >211oC (dec.)
Boiling point 586.6±50.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
storage temp. Refrigerator, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka12.08±0.70(Predicted)
form Solid
color White to Pale Beige
CAS DataBase Reference105102-22-5(CAS DataBase Reference)
Safety Information
MSDS Information
Mometasone Usage And Synthesis
Chemical PropertiesPale Yellow Solid
UsesMometasone is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders.
UsesMometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders.
DefinitionChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.
Mometasone Preparation Products And Raw materials
21-CHLORO-9,11-EPOXY-17-HYDROXY-16-METHYL-1,4- Mometasone Solvent Red 43 MOMETASONE FUROATE,MOMETASONE 17-FUROATE,MOMETASONE FUAROATE,Mometasone 17-(2-furoate) Betamethasone 17-valerate fluocortolone/mometasone/clocortolone Mesityl oxide 2-Chloro-3-hydroxypyridine 6-Methyl-5-hepten-2-one Betamethasone 21-phosphate disodium Dichloroacetic acid MOMETASONE FUROATE-D3 Allyl methacrylate Mometasone furoate USP Betamethasone N,N-Dimethylallylamine METHYLCYCLOPENTADIENE DIMER 3-Chloro-2-methylpropene

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