ChemicalBook Product Catalog Organic Chemistry Amides Sulfonic acids amino compound 2-HYDROXYSACLOFEN

2-HYDROXYSACLOFEN

2-HYDROXYSACLOFEN Basic information
Product Name:2-HYDROXYSACLOFEN
Synonyms:HYDROXYSACLOFEN;3-amino-2-(4-chlorophenyl)-2-hydroxy-*propanesulf;2-HYDROXYSACLOFEN GABA(B) RECEPTOR ANTA;3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXY-PRO PANESULFON;2-HYDROXYSACLOFEN, >99%;3-Amino-2-(4-chlorophenyl)-2-hydroxypropane-1-sulfonic acid;3-Amino-2-hydroxy-2-(4-chlorophenyl)propane-1-sulfonic acid;2-Oh-saclofen
CAS:117354-64-0
MF:C9H12ClNO4S
MW:265.71
EINECS:
Product Categories:GABA/Glycine receptor
Mol File:117354-64-0.mol
2-HYDROXYSACLOFEN Structure
2-HYDROXYSACLOFEN Chemical Properties
Melting point 267-269 °C
RTECS DA0359200
storage temp. 2-8°C
solubility H2O: 1 mg/mL
form solid
color white
Water Solubility Soluble in water at 1mg/ml. Also soluble in DMSO, 0.1M HCl and methanol
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-27-36/37/39-45
RIDADR UN 1759 8/PG 3
WGK Germany 3
HazardClass 8
MSDS Information
ProviderLanguage
SigmaAldrich English
2-HYDROXYSACLOFEN Usage And Synthesis
Uses2-Hydroxysaclofen is a GABA-B receptor antagonist in the ventral tegmental area and may play a role in the mechanisms of cocaine usage. Affects specific acute nicotine responses in mice, abolishing hypolocomotion and increasing antinociception.
DefinitionChEBI: 3-amino-2-(4-chlorophenyl)-2-hydroxy-1-propanesulfonic acid is an organochlorine compound.
Biological ActivitySelective antagonist at GABA B receptors.
storageStore at RT
2-HYDROXYSACLOFEN Preparation Products And Raw materials
2-HYDROXYSACLOFEN 5-hydroxysaclofen SACLOFEN P-CHLORO-BETA-METHYL-PHENETHYLAMINE HYDROCHLORIDE 1-AMINO-2-METHYL-PROPAN-2-OL HCL 1-AMINO-2-(4-CHLORO-PHENYL)-PROPAN-2-OL 1-AMINO-2-PHENYL-PROPAN-2-OL Ammonium 2-hydroxyethanesulphonate 2-Amino-1-(4-chlorophenyl)ethan-1-ol
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