ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Basic information
Product Name:(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
Synonyms:(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid;LCZ 696 Impurity F;LCZ704;(2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid;LCZ696696-A-C;Sacubitril Impurity 1;(αS,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1-biphenyl]-4-pentanoic Acid;Sacubitril Impurity F
CAS:1012341-54-6
MF:C23H29NO4
MW:383.48
EINECS:
Product Categories:LCZ696
Mol File:1012341-54-6.mol
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Structure
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Chemical Properties
Boiling point 582.6±50.0 °C(Predicted)
density 1.115±0.06 g/cm3(Predicted)
pka4?+-.0.23(Predicted)
Safety Information
MSDS Information
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Usage And Synthesis
Uses(αS,?γR)?-γ-?[[(1,?1-?Dimethylethoxy)?carbonyl]?amino]?-?α-?methyl-?[1,?1''-?biphenyl]?-?4-?pentanoic Acid is a useful synthetic intermediate.
(2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Preparation Products And Raw materials
(R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid Sacubitril Impurity 10 Sacubitril Impurity 16 LCZ Impurity ahu377 isomer 2 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate AHU-377 (heMicalciuM salt) LCZ696 ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate LCZ696 interMediate
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