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| | 6-Methyluracil Basic information |
| | 6-Methyluracil Chemical Properties |
| Melting point | 318 °C (dec.)(lit.) | | density | 1.226±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | pka | pK1:9.52 (25°C) | | form | Fine Crystalline Powder | | color | White to almost white | | Water Solubility | 7 g/L (22 ºC) | | Merck | 14,6133 | | BRN | 115647 | | InChIKey | SHVCSCWHWMSGTE-UHFFFAOYSA-N | | CAS DataBase Reference | 626-48-2(CAS DataBase Reference) | | NIST Chemistry Reference | 6-Methyluracil(626-48-2) | | EPA Substance Registry System | 2,4(1H,3H)-Pyrimidinedione, 6-methyl- (626-48-2) |
| | 6-Methyluracil Usage And Synthesis |
| Chemical Properties | White to Off-White Crystalline Solid | | Uses | 6-Methyluracil (cas# 626-48-2) is a compound useful in organic synthesis. | | Definition | ChEBI: A pyrimidone that is uracil with a methyl group at position 6. | | Safety Profile | Moderately toxic by
ingestion. Questionable carcinogen with
experimental neoplastigenic and teratogenic
data. Experimental reproductive effects.
When heated to decomposition it emits
toxic fumes of NOx. | | Purification Methods | Crystallise 6-methyluracil from EtOH or acetic acid. [Beilstein 24 III/IV 1281.] |
| | 6-Methyluracil Preparation Products And Raw materials |
| Raw materials | Urea-->Methyl acetoacetate-->Methylthiouracil-->4-Methyl-2,6-bis(methylsulfanyl)pyrimidine-->2,4-Imidazolidinedione, 1-acetyl-5-hydroxy- (9CI)-->1,3-dibenzyl-6-methylpyrimidine-2,4(1H,3H)-dione-->BZ-ALA-OME-->Butyl benzoate-->N,N-DIETHYLBENZAMIDE-->N-Allylmethylamine | | Preparation Products | 2,8-DICHLOROPYRIMIDO[5,4-D]PYRIMIDINE-->Orotic acid-->4,5-DIAMINO-6-METHYLPYRIMIDINE-->2,4-BIS(DIMETHYLAMINO)PYRIMIDINE-6-CARBOXYLIC ACID-->5-Nitro-6-methyluracil-->CRIMIDINE-->2,4-Dichloro-6-methyl-5-nitropyrimidine-->Potassium orotate-->4-AMINO-2-CHLORO-6-METHYL-5-NITROPYRIMIDINE-->6-CARBOXY-2,4-DIHYDROXYPYRIMIDINE MONOSODIUM SALT-->6-FORMYL-URACIL MONOHYDRATE-->4-Hydroxy-6-methylpyrimidine |
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