ChemicalBook Product Catalog Biochemical Engineering Saccharides Oligosaccharides 2,6-DI-O-METHYL-BETA-CYCLODEXTRIN

2,6-DI-O-METHYL-BETA-CYCLODEXTRIN

2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Basic information
Product Name:2,6-DI-O-METHYL-BETA-CYCLODEXTRIN
Synonyms:DIMETHYL BETA-CYCLODEXTRIN;DIMEB;HEPTAKIS(2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN;2,6-DI-O-METHYL-BETA-CYCLODEXTRIN;Dimethyl-beta-cyclodextrin, methylated beta-cyclodextrins;Di-O-methyl-β-cyclodextrin;Methyl-beta-cyclodextrin (2,6-Di-O-methyl- and partially 2,3,6-Tri-O-methyl- mixture);2,6-Dimethyl-b-cyclodextrin
CAS:51166-71-3
MF:C56H98O35
MW:1331.36
EINECS:1312995-182-4
Product Categories:Biochemistry;Cyclodextrins;Functional Materials;Macrocycles for Host-Guest Chemistry;Oligosaccharides;Sugars
Mol File:51166-71-3.mol
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Structure
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Chemical Properties
Melting point 298-310 °C
Boiling point 1203.6±65.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
refractive index 163 ° (C=1, H2O)
storage temp. Sealed in dry,Room Temperature
solubility H2O: soluble
form Crystalline Powder
pka11.63±0.70(Predicted)
color White to faintly yellow
optical activity[α]20/D +158±3°, c = 10% in H2O
Water Solubility 212.6g/L(cold water)
BRN 1679144
InChIKeyQGKBSGBYSPTPKJ-UZMKXNTCSA-N
CAS DataBase Reference51166-71-3
Safety Information
Safety Statements 24/25
WGK Germany 3
RTECS GU2293500
HS Code 29400090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN Usage And Synthesis
Chemical PropertiesWhite to faintly yellow crystalline powder
UsesInduces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods
UsesReactant involved in:
  • Physicochemical studies of inclusion complexes
  • Probing diffusion and single molecule interactions with reconstituted membrane proteins
  • Interactions with micelles causing micellar rupture
  • Studying cellular transport, used as a cell penetration enhancer
  • Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability
  • Interactions with cholesterol
General DescriptionHeptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds.
2,6-DI-O-METHYL-BETA-CYCLODEXTRIN HEPTAKIS-(2 3 6-TRI-O-ETHYL)-BETA- HEPTAKIS(2,3,6-TRI-O-''OCTYL)-BETA-CYCLODEXTRIN HEPTAKIS-(3-O-TRIFLUOROACETYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN HEPTAKIS-(3-O-BUTYRYL-2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN DI-O-METHYL-BETA-CYCLODEXTRIN Heptakis-(2,6-di-O-butyl-3-O-acetyl)-beta-Cyclodextrin HEPTAKIS(2,6-DI-O-''BUTYL)-BETA-CYCLODEXTRIN**** TRIMETHYL-BETA-CYCLODEXTRIN HEPTAKIS(2,6-DI-O-METHYL-3-O-''PENTYL)-BETA-CYCLODEXTRIN* HEPTAKIS(3-O-ALLYL-2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN HEPTAKIS(3-O-ALLYL-2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN = ALLYLDIMEBETA HEPTAKIS-(2,6-DI-O-PENTYL)-BETA-CYCLODEXTRIN HEPTAKIS(3-O-ACETYL-2,6-DI-O-METHYL)-BETA-CYCLODEXTRIN Heptakis-(2,6-di-O-pentyl-3-O-acetyl)-beta-Cyclodextrin TRIACETYL-BETA-CYCLODEXTRIN 3-O-TRIFLUOROACETYLPERMETHYL-BETA-CYCLODEXTRINE HEPTAKIS(3-O-ACETYL-2 6-DI-O-METHYL)-
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