4-Amino-3-methoxybenzoic acid

4-Amino-3-methoxybenzoic acid Basic information

Product Name:	4-Amino-3-methoxybenzoic acid
Synonyms:	4-AMINO-3-METHOXYBENZOIC ACID;3-METHOXY-4-AMINOBENZOIC ACID;TIMTEC-BB SBB008622;4-amino-m-anisic acid;o-anisidine-4-carboxylic acid;4-AMINO-3-METHOXYBENZOIC ACID 99%;4-Amino-3-methoxybenzoic acid,98%;4-AMino-3-Methoxybenzoic acid, 98% 5GR
CAS:	2486-69-3
MF:	C8H9NO3
MW:	167.16
EINECS:
Product Categories:	Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Heterocyclic Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;Aromatic Amino Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives
Mol File:	2486-69-3.mol

4-Amino-3-methoxybenzoic acid Chemical Properties

Melting point	186-188 °C (lit.)
Boiling point	357.9±27.0 °C(Predicted)
density	1.303±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	4.74±0.10(Predicted)
form	Powder, Crystals and/or Chunks or Fused Solid
color	White to cream to pale yellow
InChIKey	JNFGLYJROFAOQP-UHFFFAOYSA-N
CAS DataBase Reference	2486-69-3(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
Hazard Note	Irritant
HS Code	29225090

MSDS Information

Provider	Language
SigmaAldrich	English

4-Amino-3-methoxybenzoic acid Usage And Synthesis

Chemical Properties	Grey powder
Uses	4-Amino-3-methoxybenzoic Acid is an intermediate used to prepare (aminophenyl)benzothiazoles with antitumor activities. It is also used to synthesize (phenyl)(cyanopyrazinyl)urea derivatives as checkpoint kinase-1 (Chk1) inhibitors.
Uses	Key building block for the efficient synthesis of carbazole alkaloids mukonine and mukonidine via oxidative annulation.

4-Amino-3-methoxybenzoic acid Preparation Products And Raw materials

Raw materials	3-Methoxy-4-nitrobenzoic acid-->3-Hydroxy-4-nitrobenzoic acid-->Vanillic acid-->3-Methoxybenzoic acid
Preparation Products	7-Methoxy-1H-indole-->4-Iodo-3-methoxybenzenecarboxylic acid-->[4-[[5-Chloro-4-(MethylaMino)-2-pyriMidinyl]aMino]-3-Methoxyphenyl]-4-MorpholinylMethanone-->Methyl 4-amino-3-methoxybenzoate-->6-Quinolinecarboxylic acid, 8-methoxy-, ethyl ester-->BOC-4-AMINO-3-METHOXYBENZOIC ACID

METHYL 3-[(4-METHYLBENZOYL)OXY]-4-NITROBENZENECARBOXYLATE BOC-3-AMINO-4-METHOXYBENZOIC ACID AURORA KA-6179 4-Amino-3-propoxy-benzoic acid 2-(diethylamino)ethyl ester hydrochlori de 3-(N-(TERT-BUTOXYCARBONYL)AMINO)-4-METHOXYBENZOIC ACID 5-(METHOXYCARBONYL)-2-NITROPHENYL 2-THIOPHENECARBOXYLATE BOC-5-AMINO-2-METHOXYBENZOIC ACID AURORA 1315 3-Methylanthranilic acid 3-butoxy-4-aminobenzoic acid Methyl 3-methoxy-4-nitrobenzoate FMOC-3-AMINO-4-METHOXYBENZOIC ACID 3-BUTOXY-4-NITROBENZOIC ACID 4-AMINO-3-METHOXYBENZOIC ACID ETHYL ESTER METHYL 3-[(2-FLUOROBENZOYL)OXY]-4-NITROBENZENECARBOXYLATE 5-AMINO-2-METHOXYBENZOIC ACID BOC-4-AMINO-3-METHOXYBENZOIC ACID Butyl 4-aminobenzoate

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