Everolimus Ring-Opening Impurity

Everolimus Ring-Opening Impurity Basic information
Product Name:Everolimus Ring-Opening Impurity
Synonyms:EverolimusRetroaldolDegradationProduct;(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy);Everolimus Impurity 012-99;Everolimus Open-Ring Impurity;Everolimus Open-Ring Aldehyde Impurity;Everolimus Impurity 33;(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate;(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate
CAS:1708118-13-1
MF:C53H83NO14
MW:958.22442
EINECS:
Product Categories:
Mol File:1708118-13-1.mol
Everolimus Ring-Opening Impurity Structure
Everolimus Ring-Opening Impurity Chemical Properties
Melting point 45-50°C
storage temp. Amber Vial, -86°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability:Light and temperature Sensitive
Safety Information
MSDS Information
Everolimus Ring-Opening Impurity Usage And Synthesis
UsesEverolimus Retroaldol Degradation Product is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Everolimus Impurity D
Everolimus Ring-Opening Impurity Preparation Products And Raw materials
2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone Rapamycin 28-epirapamycin 2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate Everolimus Hydrolized Impurity Seco Rapamycin Rapamycin, 32-O-demethyl- Everolimus Related Compound 2 EveroliMus iMpurity EveroliMus-d4 Everolimus Related Compound 3 Everolimus O-Ethyl Impurity 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Everolimus Impurity 1 USDOYNAPNXMXOE-SPSCNLKESA-N Everolimus EP Impurity E Everolimus Ring-Opening Impurity Everolimus

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