5-Oxo Pitavastatin

5-Oxo Pitavastatin Basic information
Product Name:5-Oxo Pitavastatin
Synonyms:5-Oxo Pitavastatin;Pitavastatin impurity 5/5-Oxo Pitavastatin;Pitavastatin 5-Oxo Acid;(R,E)-7-(2-cyclopropyl;Pitavastatin Impurity 25 (5-Oxo Pitavastatin);6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-, (3R,6E)-;Monocalciumbis[(R,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3-hydroxy-5-oxohept-6-enoate];Pitavastatin Impurity 7 Sodium Salt
CAS:222306-15-2
MF:C25H22FNO4
MW:419.44
EINECS:
Product Categories:Aromatics, Heterocycles, Inhibitors, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:222306-15-2.mol
5-Oxo Pitavastatin Structure
5-Oxo Pitavastatin Chemical Properties
Melting point 101-106°C
Boiling point 655.1±55.0 °C(Predicted)
density 1.349±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.18±0.10(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
5-Oxo Pitavastatin Usage And Synthesis
Uses5-Oxo Pitavastatin is a metabolite of Pitavastatin, a competitive inhibitor of HMG-CoA reductase and is a known antilipemic agent.
5-Oxo Pitavastatin Preparation Products And Raw materials
Pitavastatin Methyl Ester (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid CalciuM Salt Pitavastatin Impurity 18 Sodium Salt Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate Pivastatin amide impurity Pitavastatin Ethyl Ester Tert-buthyl Pitavastatin (3R,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid CalciuM Salt Pitavastatin calcium Desfluoro Pitavastatin Calcium

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