Axitinib Impurity B

Axitinib Impurity B Basic information

Product Name:	Axitinib Impurity B
Synonyms:	2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide;BenzaMide, 2-(1H-indazol-6-ylthio)-N-Methyl-;Axitinib Impurity e;Axitinib impurity G;Axitinib Impurity 3/2-((1H-indazol-6-yl)thio)-N-methylbenzamide;2-(1H-Indazol-6-ylsulfanyl)-N-methylbenzamide
CAS:	944835-85-2
MF:	C15H13N3OS
MW:	283.35
EINECS:
Product Categories:	Intermediate
Mol File:	944835-85-2.mol

Axitinib Impurity B Chemical Properties

Melting point	>148°C (dec.)
Boiling point	555.7±30.0 °C(Predicted)
density	1.36±0.1 g/cm3(Predicted)
storage temp.	4°C, Inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka	13.02±0.40(Predicted)
form	Solid
color	White to Off-White

Safety Information

MSDS Information

Axitinib Impurity B Usage And Synthesis

Uses	2-(1H-Indazol-6-ylthio)-N-methylbenzamide is a useful intermediate for the preparation of axitinib; an antitumor agent.

Axitinib Impurity B Preparation Products And Raw materials

Raw materials	6-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-->6-Aminoindazole-->6-IODO (1H)INDAZOLE-->2,2'-dithiobis[N-methylbenzamide]-->N-methyl-2-sulfanylbenzamide-->2,2'-dithiodibenzoyl chloride-->2,2'-Dithiosalicylic acid
Preparation Products	BenzaMide, 2-[(3-iodo-1H-indazol-6-yl)thio]-N-Methyl-

Axitinib Impurity a Axitinib Impurity 27 Axitinib-13C-d3 Axitinib Impurity 13 Axitinib Impurity 18 Axitinib Impurity 20 Axitinib Impurity d Axitinib Impurity 4 Axitinib Impurity 10 Axitinib Impurity 26 Axitinib Impurity 3 Axitinib Impurity 23 Axitinib N-Glucuronide (M7) Axitinib Impurity 3 Axitinib Impurity 30 Axitinib Impurity 14 Axitinib Impurity 19 Axitinib Impurity 32

Email:[email protected] [email protected]

Copyright © 2024 Mywellwork.com All rights reserved.