Ticagrelor Sulfone

Ticagrelor Sulfone Basic information
Product Name:Ticagrelor Sulfone
Synonyms:(1S,2S,3R,5S)-3-(7-(((1R,2R)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolcompound with (1S,2S,3R,5S)-3-(7-(((1S,2S)-2-(3,4-difluorophenyl)cy;Ticagrelor DP5;Ticagrelor impurity 39/(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl) amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl) -5-(2-hydroxyethoxy)cyclopentane-1,2-diol;Ticagrelor-29;1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]aMino]-5-(propylsulfonyl)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-;Ticagrelor Sulfone;Ticagrelor Sulfone Impurity;(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylsulfonyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
CAS:274693-39-9
MF:C23H28F2N6O6S
MW:554.57
EINECS:
Product Categories:
Mol File:274693-39-9.mol
Ticagrelor Sulfone Structure
Ticagrelor Sulfone Chemical Properties
Melting point 153-156°C
Boiling point 819.5±75.0 °C(Predicted)
density 1.74±0.1 g/cm3(Predicted)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Very Slightly)
pka13.22±0.70(Predicted)
form Solid
color White to Off-White
Stability:Light Sensitive
Safety Information
MSDS Information
Ticagrelor Sulfone Usage And Synthesis
UsesTicagrelor Sulfone is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
Ticagrelor Sulfone Preparation Products And Raw materials
(trans)-2-(3,4-difluorophenyl)cyclopropanecarboxamide Ticagrelor diastereoMer Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[[5-aMino-6-chloro-2-(propylthio)-4-pyriMidinyl]aMino]tetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]- Ticagrelor Related Compound 71 Ticagrelor Related Compound 94 HCl TICAGRELOR (1R,2S)-2-(3,4-difluorophenyl)cyclopropanaMine hydrochloride Ticagrelor Related Compound 15 Ticagrelor Related Compound 70 HCl (3aS,4R,6S,6aR)-6-AMinotetrahydro-2,2-diMethyl-4H-cyclopenta-1,3-dioxol-4-ol Ticagrelor (1S,2S,3R,5S)-3-(7-((1S,2R)-2-(3,4-difluorophenyl)cyclopropylaMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol Ticagrelor Related Compound 38D-Tartrate 2-[[(3aS,4R,6S,6aR)-4-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol CyclopropanaMine, 2-(4-fluorophenyl)-(hydrochloride)(1:1),(1R,2S)- Ticagrelor Impurity 15 6-chloro-N-((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)-5- nitro-2-(propylthio)pyrimidin-4-amine 3-((3aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro- 4H-cyclopenta[d][1,3]dioxol-4-yl)-5-(propylthio)-3H-[1,2,3] triazolo[4,5-d]pyrimidin-7-ol

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