ChemicalBook Product Catalog Biochemical Engineering Inhibitors PI3K / Akt / mTOR Akt inhibitors AKT Kinase Inhibitor

AKT Kinase Inhibitor

AKT Kinase Inhibitor Basic information
Product Name:AKT Kinase Inhibitor
Synonyms:AKT Kinase Inhibitor;3-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-propyn-1-ol;2-Propyn-1-ol, 3-[2-(4-aMino-1,2,5-oxadiazol-3-yl)-7-(3-aMinopropoxy)-1-ethyl-1H-iMidazo[4,5-c]pyridin-4-yl]-;AKT Kinase Inhibitor (2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-);3-[2-(4-amino-1;5-c]pyridin-4-yl]-;5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4;AKT Kinase Inhibitor USP/EP/BP
CAS:842148-40-7
MF:C16H19N7O3
MW:357.37
EINECS:
Product Categories:
Mol File:842148-40-7.mol
AKT Kinase Inhibitor Structure
AKT Kinase Inhibitor Chemical Properties
Boiling point 678.8±65.0 °C(Predicted)
density 1.50
storage temp. Store at -20°C
solubility DMSO : 16.67 mg/mL (46.65 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka12.98±0.10(Predicted)
Safety Information
MSDS Information
AKT Kinase Inhibitor Usage And Synthesis
Biological ActivityAKT Kinase Inhibitor is an Akt inhibitor with antitumor activity.
in vivo

Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus.

target

Akt

AKT Kinase Inhibitor Preparation Products And Raw materials
6-Mercaptopurine AKTI-1/2 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
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