TriMethyl(broModifluoroMethyl)silane

TriMethyl(broModifluoroMethyl)silane Basic information

Product Name:	TriMethyl(broModifluoroMethyl)silane
Synonyms:	(Bromodifluoromethyl)trimethylsilane 98%;TriMethyl(broModifluoroMethyl)silane;Bromodifluoro(trimethylsilyl)methane;(Bromodifluoromethyl);Trimethyl(bromodifluoromethyl)silane 97%;(Bromodifluoromethyl)trimethylsilane >;Silane, (bromodifluoromethyl)trimethyl-;Difluorobromomethylsilane
CAS:	115262-01-6
MF:	C4H9BrF2Si
MW:	203.1
EINECS:	806-938-4
Product Categories:
Mol File:	115262-01-6.mol

TriMethyl(broModifluoroMethyl)silane Chemical Properties

Boiling point	108°C(lit.)
density	1.306
refractive index	n/D1.407
Fp	46℃
storage temp.	-20°C
form	liquid
color	clear
InChIKey	WDZVWBWAUSUTTO-UHFFFAOYSA-N
CAS DataBase Reference	115262-01-6

Safety Information

MSDS Information

TriMethyl(broModifluoroMethyl)silane Usage And Synthesis

Uses	Novel difluorocarbene source for the efficient difluoromethylenation of alkenes/alkynes and difluoromethylation of O-, S-, and N-nucleophiles.
Uses	Trimethyl(bromodifluoromethyl)silane can be used as neuroactive steroids.
Uses	As reported by Hu and co-workers, (Bromodifluoromethyl)trimethylsilane is a highly useful reagent for the formation of difluoromethene-containing 3-membered rings and can also difluoromethylate heteroatoms with the assistance of alkaline bases, most effectively KOH.
General Description	(Bromodifluoromethyl)trimethylsilane (TMSCF₂Br) is commonly used as a source to generate dilfluorocarbene. TMSCF₃ (Ruppert–Prakash reagent) and BBr₃ undergoes fast halogen–exchange reaction to form MSCF₂Br.

TriMethyl(broModifluoroMethyl)silane Preparation Products And Raw materials

Raw materials	(chlorodifluoroMethyl)triMethylsilane-->DIBROMODIFLUOROMETHANE-->(Difluoromethyl)trimethylsilane-->Bromotrimethylsilane-->(Trifluoromethyl)trimethylsilane-->Chlorotrimethylsilane
Preparation Products	BROMODIFLUOROMETHANE-->(Difluoromethyl)trimethylsilane-->[(difluoromethyl)thio]benzene-->benzyl 2-(difluoromethoxy)acetate

Login