17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid

17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid Basic information
Product Name:17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid
Synonyms:AEEA-AEEA;8-Amino-3,6-dioxaoctanoic acid dimer≥ 98% (HPLC);H-Adoa-Adoa-OH;2-[2-[2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]ethoxy]ethoxy]acetic acid;17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan;7-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadeca;H2N-PEG2-CH2CONH-PEG2-CH2COOH;17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oicaci
CAS:1143516-05-5
MF:C12H24N2O7
MW:308.33
EINECS:
Product Categories:1143516-05-5;ADC LINKER
Mol File:1143516-05-5.mol
17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid Structure
17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid Chemical Properties
Melting point 133 - 135°C
Boiling point 548.7±50.0 °C(Predicted)
density 1.202±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
pka3.39±0.10(Predicted)
form Solid
color White to Off-White
InChIInChI=1S/C12H24N2O7/c13-1-3-18-5-7-20-9-11(15)14-2-4-19-6-8-21-10-12(16)17/h1-10,13H2,(H,14,15)(H,16,17)
InChIKeyYQZVQKYXWPIKIX-UHFFFAOYSA-N
SMILESC(O)(=O)COCCOCCNC(=O)COCCOCCN
CAS DataBase Reference1143516-05-5
Safety Information
HS Code 2924190090
MSDS Information
17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid Usage And Synthesis
Chemical PropertiesWhite crystalline powder
Uses17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is used for preparation of glutamic acid-containing acylating reagents for selective acylation of amino group(s) in peptides or proteins.
Synthesis17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid is synthesized by Hydrolysis Reaction of 12,12-Dimethyl-10-oxo-3,6,11-trioxa-9-azatridecanoic acid  with Hydrolysis Reaction in Dichloromethane for 2h.
17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid Preparation Products And Raw materials
Raw materials17-(t-Butyloxycarbonyl-amino)-9-aza-3,6,12,15-tetraoxa-10-on-heptadecanoic acid
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL BOC-8-AMINO-3,6-DIOXAOCTANOIC ACID DCHA 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid H2N-PEG8-OH (Tert-Butoxy)Carbonyl L-His(Trt)-Aib-OH Amino-PEG6-alcohol Fmoc-L-Lys[Oct-(otBu)-Glu-(otBu)-AEEA-AEEA]-OH H2N-PEG12-OH 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic Acid

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