2,2'-Methylene Bis[Ranitidine]

2,2'-Methylene Bis[Ranitidine] Basic information
Product Name:2,2'-Methylene Bis[Ranitidine]
Synonyms:2,2'-Methylene Bis[Ranitidine];N1,N5-Bis[2-[[[5-[(diMethylaMino)Methyl]-2-furanyl]Methyl]thio]ethyl]-N1',N5'-diMethyl-2,4-dinitro-1,4-pentadiene-1,1,5,5-tetraMine;Ranitidine IMpurity I;Bis[N-[2-[[[5-[(dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-N'-methyl-2,2-diamino-1-nitroethenyl]methane;Randitidine EP IMP I;Ranitidine Impurity I(EP) (a dimer);Ranitidine EP Impurity I;Ranitidine Impurity I (EP)
CAS:207592-21-0
MF:C27H44N8O6S2
MW:640.82
EINECS:
Product Categories:Amines;Heterocycles;Impurities;Sulfur & Selenium Compounds
Mol File:207592-21-0.mol
2,2'-Methylene Bis[Ranitidine] Structure
2,2'-Methylene Bis[Ranitidine] Chemical Properties
Melting point >47°C (dec.)
Boiling point 822.0±65.0 °C(Predicted)
density 1.235±0.06 g/cm3(Predicted)
storage temp. Amber Vial, -86°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka8.65±0.28(Predicted)
form Solid
color Pale Yellow to Dark Brown
Stability:Light Sensitive, Temperature Sensitive
Safety Information
MSDS Information
2,2'-Methylene Bis[Ranitidine] Usage And Synthesis
Uses2,2’-Methylene Bis[Ranitidine] (Ranitidine EP Impurity I) is an impurity of histamine H2-receptor antagonist Ranitidine (R120000).
2,2'-Methylene Bis[Ranitidine] Preparation Products And Raw materials
N-METHYL-2-NITROACETAMIDE 5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furfurylamine N,N'-BIS[2-[5-(DIMETHYLAMINOMETHYL)FURFURYLTHIO]ETHYL]-2-NITRO-1,1-ETHENDIAMINE N-[2-[5-(DIMETHYLAMINOMETHYL)-2-FURFURYLTHIO]ETHYL]-2-NITRO-ACETAMIDE SODIUM SALT Ranitidine Hydrochloride RANITIDINE-N-OXIDE Ranitidine Ranitidine hydrochloride RANITIDINE IMPURITY C 5,6-Dihydro-3-(MethylaMino)-2H-1,4-thiazin-2-one OxiMe Hydrochloride Ranitidine impurity B (PhEur) 5-(DIMETHYLAMINOMETHYL)FURFURYL ALCOHOL HYDROCHLORIDE 1,1'-N-[Methylenebis(sulphanediylethylene)]bis(N'-Methyl-2-nitroethene-1,1-diaMine N-Methyl-1-(methylthio)-2-nitroethylen-1-amine

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