ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL

(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL

(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Basic information
Product Name:(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL
Synonyms:(1R)-3-(Methylamino)-1-(2-thienyl)-1-propanol;(R)-3-(Methylamino)-1-(thiophen-2-yl)propan-1-ol;(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL;Duloxetine Impurity 17;(R)-3-Methylamino-1-(2-thienyl)-1-propanol;N-Methyl[(R)-3-hydroxy-3-(2-thienyl)propyl]amine;2-Thiophenemethanol, α-[2-(methylamino)ethyl]-, (αR);(1R)-3-(methylamino)-1-thiophen-2-ylpropan-1-ol
CAS:116539-57-2
MF:C8H13NOS
MW:171.26
EINECS:
Product Categories:
Mol File:116539-57-2.mol
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Structure
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Chemical Properties
Boiling point 294.3±35.0 °C(Predicted)
density 1.128
storage temp. 2-8°C(protect from light)
pka13.77±0.20(Predicted)
Safety Information
MSDS Information
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Usage And Synthesis
Uses(R)-3-Methylamino-1-(2-thienyl)-1-propanol is a reactant used in the synthesis of enantiomerically pure Duloxetine (D721000), an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
(R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL Preparation Products And Raw materials
(S)-3-(MethylaMino)-1-(2-thienyl)-1-propanol (S)-Duloxetine SuccinaMide 3-THIOPHENEPROPANAMINE, N,N-DIMETHYL-GAMMA-(1-NAPHTHALENYLOXY)-, ETHANEDIOATE(1:1) 3-(Dimethylamino)-1-(2-thienyl)-1-propanol (RS)-4-(3-MethylaMino-1-thiophen-2-yl-propyl)-naphthalen-1-ol (R)-(+)-3-(N-METHYLAMINO)-1-(2-THIENYL)-1-PROPANOL 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-ISOPROPYLPIPERIDINE 4-HYDROXY-4-(2-THIENYL)-1-METHYLPIPERIDINE 4-HYDROXY-4-(2-THIENYL)-1-ISOPROPYLPIPERIDINE 4-HYDROXY-4-(5-METHYL-2-THIENYL)-1-METHYLPIPERIDINE (R)-Duloxetine 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-ISOPROPYLPIPERIDINE AKOS 91515 AKOS 91503 4-(2-CHLORO-5-THIENYL)-4-HYDROXY-1-METHYLPIPERIDINE AKOS 94342 AKOS 94343 AKOS 91648
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