ChemicalBook Product Catalog Chemical Reagents Organic reagents Guanidine salt ZONIPORIDE

ZONIPORIDE

ZONIPORIDE Basic information
Product Name:ZONIPORIDE
Synonyms:N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;CP 597396;ZONIPORIDE;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate;Zoniporide hydrochloride hydrate;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide
CAS:241800-98-6
MF:C17H16N6O
MW:320.35
EINECS:
Product Categories:
Mol File:241800-98-6.mol
ZONIPORIDE Structure
ZONIPORIDE Chemical Properties
density 1.54
storage temp. 2-8°C
solubility H2O: soluble2mg/mL, clear (warmed)
form powder
pka11.44±0.46(Predicted)
color white to tan
Safety Information
WGK Germany 3
MSDS Information
ZONIPORIDE Usage And Synthesis
UsesZoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.
Biochem/physiol ActionsZoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.
ZONIPORIDE Preparation Products And Raw materials
ZONIPORIDE 5-METHYL-1-PHENYL-(1H-PYRAZOL-4-YLMETHYL)AMINE HYDROCHLORIDE 5-ISOPROPYL-1-PHENYL-1H-PYRAZOLE
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.