ChemicalBook Product Catalog Biochemical Engineering Chinese Herbs Cephalomannine

Cephalomannine

Cephalomannine Basic information
Product Name:Cephalomannine
Synonyms:TAXOL B;BENZENEPROPANOICACID,ALPHA-HYDROXY-BETA-[(2-METHYL-1-OXO-2-BUTENYL)AMINO]-,6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA[3,4]BENZ[1,2-;BENZENEPROPANOIC ACID, ALPHA-HYDROXY-BETA-[(2-METHYL-1-OXO-2-BUTENYL)AMINO]-,6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA[3,4]BENZ[1,2-B]OXET-9-YL ESTER,[2AR-[2A,4,4A,6,9[R*,S*(E)],11,12,12A,12B]]-;CEPHALOMANNINE;paclitaxel iMpurity I;CephaloMannine, froM Taxus chinensis;(αR,βS)-α-Hydroxy-β-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]aMino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)- 12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester;NSC 318735
CAS:71610-00-9
MF:C45H53NO14
MW:831.9
EINECS:
Product Categories:Inhibitors;Alkaloids;Antineoplastic and Immunosuppressive AntibioticsEnzyme Inhibitors by Enzyme;DNA polymerase - alphaAntibiotics;Antibiotics;Antibiotics A to;Antibiotics A-FAntibiotics;Antibiotics by Application;Chemical Structure Class;D to;Interferes with DNA SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Herb extract;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Impurities
Mol File:71610-00-9.mol
Cephalomannine Structure
Cephalomannine Chemical Properties
Melting point 139-141?C
Boiling point 929.5±65.0 °C(Predicted)
density 1.36±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO: 14 mg/mL, soluble
pka11.95±0.20(Predicted)
form solid
color White to Pale Beige
InChIKeyDBXFAPJCZABTDR-WBYYIXQISA-N
CAS DataBase Reference71610-00-9
Safety Information
Hazard Codes Xi
Risk Statements 37/38-41
Safety Statements 26-39
WGK Germany 3
HS Code 29329990
MSDS Information
ProviderLanguage
SigmaAldrich English
Cephalomannine Usage And Synthesis
Chemical PropertiesOff-White Solid
OccurrenceA taxane derivative, cephalomannine occurs in the extract of Cephalotaxus rnannii. It has been obtained as colourless needles from MeOH aq. and is laevorotatory with a specific rotation of [α]D -41° (MeOH).
UsesCephalomannine is an active anti-cancer agent obtained from Taxus yunnanensis and has an antineoplastic effect on tumors found in mice. Cephalomannine is a chemotherapy drug that is given as a treatment for some types of cancer. Cephalomannine is most com
UsesAntitumor, antiproliferative.
Usessimilar anti-cancer function as Taxol
Cephalomannine Preparation Products And Raw materials
Raw materialsTIGLOYL CHLORIDE
(2R,3S)-3-PHENYLISOSERINE ETHYLESTER Cephalomannine 2,6,6-trimethylcyclohexene-1-methanol Homoharringtonine 1,2-CYCLODODECANEDIOL 1-METHYLCYCLODODECYL METHYL ETHER CYCLOOCTANONE TRANS-1,2-CYCLOOCTANEDIOL CYCLODODECYL FORMATE (R)-3-Amino-3-phenylpropionicacidethylester Oxetan-3-ol cyclododecyl acetate ISO-PROPYLIDENECYCLOOCTANE 2,6,6-TRIMETHYL-1-CYCLOHEXENE-1-ACETALDEHYDE (R,R)-(-)-1,2-CYCLODODECANEDIOL 1-METHYLIDENECYCLODODECANE D-(+)-Phenyllactic acid LACTIC ACID TETRADECYL ESTER
Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.