2-Aminobenzotrifluoride

2-Aminobenzotrifluoride Basic information
Product Name:2-Aminobenzotrifluoride
Synonyms:2-(Trifluoromethyl)aniline,α,α,α-Trifluoro-o-toluidine, 2-Aminobenzotrifluoride;2-Aminobenzotrifluor;2-(Trifluoromethyl)aniline alpha,alpha,alpha-Trifluoro-o-toluidine;2-AMINOBENZOTRIFLUORIDE FOR SYNTHESIS;The three adjacenttrifluoroMethylaniline;2-(TrifluoroMethyl)aniline 99%;2-(TrifluoroMethyl)aniline, 97+%;Neighboring aMino trifluoro toluene
CAS:88-17-5
MF:C7H6F3N
MW:161.12
EINECS:201-806-7
Product Categories:Anilines, Aromatic Amines and Nitro Compounds;Aromatic Halides (substituted);Amines;Building Blocks;C7;Chemical Synthesis;API intermediates;Nitrogen Compounds;Organic Building Blocks;amine;Pyridines
Mol File:88-17-5.mol
2-Aminobenzotrifluoride Structure
2-Aminobenzotrifluoride Chemical Properties
Melting point 34 °C(lit.)
Boiling point 170-173 °C(lit.)
density 1.282 g/mL at 25 °C(lit.)
vapor pressure 2.1-12.1hPa at 20-50℃
refractive index n20/D 1.481(lit.)
Fp 131 °F
storage temp. Store below +30°C.
solubility 4g/l
pka1.10±0.10(Predicted)
form Liquid
color Clear colorless to light amber
Specific Gravity1.282
Water Solubility 4 g/L (20 ºC)
BRN 879494
LogP2.32 at 23℃ and pH7
CAS DataBase Reference88-17-5(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenamine, 2-(trifluoromethyl)-(88-17-5)
EPA Substance Registry Systemo-(Trifluoromethyl)aniline (88-17-5)
Safety Information
Hazard Codes T,Xi,Xn,F
Risk Statements 10-23/24/25-33-36/37/38-22-20/21/22
Safety Statements 36/37/39-45-37/39-26-16-36
RIDADR UN 2942 6.1/PG 3
WGK Germany 1
RTECS XU9210000
Hazard Note Toxic/Irritant
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29214300
MSDS Information
ProviderLanguage
2-(Trifluoromethyl)aniline English
ACROS English
SigmaAldrich English
ALFA English
2-Aminobenzotrifluoride Usage And Synthesis
Chemical Propertiesclear colorless to light amber liquid
Useso-Aminobenzotrifluoride-d2 is a 4-substituted aniline derivative that exerts special hematotoxicity on red blood cells and induce leukocytosis. o-Aminobenzotrifluoride-d2 is a thiohydrazides used as an antibacterial remedy for Chlamydial infection treatment at chronic stages of infections.
General DescriptionA colorless liquid with a fishlike odor. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.
Air & Water ReactionsInsoluble in water.
Reactivity Profile2-Aminobenzotrifluoride is a halogenated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health HazardTOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardCombustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
2-(Trifluoromethyl)benzoic acid 4-Bromobenzotrifluoride Benzotrifluoride o-Xylene 2,3-DIAMINOTOLUENE 3,3',5,5'-Tetramethylbenzidine dihydrochloride 4-(Trifluoromethoxy)aniline N,N-Dimethyl-p-toluidine 5-Chloro-2-aminobenzotrifluoride 1,4-Bis(trifluoromethyl)-benzene Trifluoromethyl 3-Fluorobenzotrifluoride 2-Fluoroaniline o-Toluidine Aniline 2-(Trifluoromethoxy)aniline 2,5-Bis(trifluoromethyl)aniline 3-Aminobenzotrifluoride;3-(Trifluoromethyl)aniline

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