6-Methoxyguanine

6-Methoxyguanine Basic information
Product Name:6-Methoxyguanine
Synonyms:O6-METHYLGUANINE;O-METHYLGUANINE;2-amino-6-methoxy-purin;6-methoxy-1h-purin-2-amin;6-methoxy-1h-purine-2-amine;o(sup6)-methylguanine;6-Methoxyguanine;6-methoxy-1h-purin-2-amine
CAS:20535-83-5
MF:C6H7N5O
MW:165.15
EINECS:606-576-5
Product Categories:Bases & Related Reagents;Intermediates & Fine Chemicals;Amines;Nucleotides;Pharmaceuticals;Fused Ring Systems;Purine;Chemical Amines;Purines;Intermediate in the synthesis of Tropine and respective derivatives
Mol File:20535-83-5.mol
6-Methoxyguanine Structure
6-Methoxyguanine Chemical Properties
Melting point >300 °C(lit.)
Boiling point 598.5±53.0 °C(Predicted)
density 1.531±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly, Heated), Water (Slightly, Heated)
pka9.74±0.10(Predicted)
form Solid
color Off-White to Pale Yellow
BRN 645384
InChIKeyBXJHWYVXLGLDMZ-UHFFFAOYSA-N
CAS DataBase Reference20535-83-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
RTECS UO7473000
Hazard Note Irritant
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
6-Methoxyguanine Usage And Synthesis
Chemical PropertiesOff-white solid
UsesAntitumor agent
UsesThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
DefinitionChEBI: A methylguanine in which the methyl group is positioned on the oxygen at position 6. Formed in DNA by alkylation of the oxygen atom of guanine, most often by N-nitroso compounds and sometimes due to methylation by other compounds such as endogenous S-adenosylmethionine, it base-pairs to thymine rather than cytidine, causing a G:C to A:T transition in DNA.
General DescriptionPharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
6-Methoxyguanine Preparation Products And Raw materials
Preparation ProductsAcyclovir
Nelarabine 6-Methoxyguanine DIPHENYL-CARBAMIC ACID(2-ISOBUTYRYL GUANINE) ESTER N2-ACETYL-O6-(DIPHENYLCARBAMOYL)GUANINE O6-BENZYL-8-BROMO-N9-[3',5'-O-(1,1,3,3-TETRAKIS(ISOPROPYL)-1,3-DISILOXANEDIYL)-BETA-D-2'-DEOXYRIBOFURANOSYL]GUANINE O(6)-methyldeoxyguanosine triphosphate O6-METHYL-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT 2-((4-Butylphenyl)amino)-6-methoxy-9H-purine Triallylamine 6-Aminocaproic acid O6-METHYL-2'-DEOXYGUANOSINE N2-(1,1,4,4-TETRAMETHYLDISILYLAZACYCLOPENTANYL)-O6-BENZYL-8-BROMO-N9-[3',5'-O-(1,1,3,3-TETRAKIS(ISOPROPYL)-1,3-DISILOXANEDIYL)-BETA-D-2'-DEOXYRIBOFURANOSYL]GUANINE O6-METHYLGUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT 6-O-Methyl Guanosine Tris(hydroxymethyl)aminomethane AMINO ACIDS 3-Aminophenol 6-O-Benzylguanine

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