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| | CINCHONINE HYDROCHLORIDE Basic information |
| | CINCHONINE HYDROCHLORIDE Chemical Properties |
| Melting point | 208-218 °C(lit.) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | CAS DataBase Reference | 5949-11-1 |
| | CINCHONINE HYDROCHLORIDE Usage And Synthesis |
| Description | Cinchonine hydrochloride not only possesses the required solubility and bioavailability criteria for pharmaceutical formulations while retaining desired therapeutic properties, but is also very stable in solution, which facilitates the preparation of aqueous formulations, especially injections. | | Uses | Cinchonine hydrochloride can be used as an inhibitory substance for the phenomenon of "multidrug resistance" (MDR). In particular, cinchonine hydrochloride compositions are useful in the treatment of cancer-related diseases with MDR phenomena. | | Biological Activity | Cinchonine hydrochloride ((8R,9S)-Cinchonine hydrochloride) is a natural compound in cinchona bark with antimalarial activity. It can activate endoplasmic reticulum stress to induce apoptosis in human hepatoma cells. |
| | CINCHONINE HYDROCHLORIDE Preparation Products And Raw materials |
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