ChemicalBook Product Catalog Organic Chemistry Ketones 2-Hydroxy-2-methylpropiophenone

2-Hydroxy-2-methylpropiophenone

2-Hydroxy-2-methylpropiophenone Basic information
Uses
Product Name:2-Hydroxy-2-methylpropiophenone
Synonyms:1-Propanone, 2-hydroxy-2-methyl-1-phenyl-;ACETOCURE 73;1-Phenyl-2-hydroxy-2-methylpropane-1-one;1-Phenyl-2-methyl-2-hydroxy-1-propanone;1-Phenyl-2-(hydroxymethyl)-1-propanone;1-Hydroxy-1-methylethyl phenyl ketone;2-Hydroxy-2-Methyl-1-phenyl-1-Porpanone;alpha-Hydroxyisobutyrophenone
CAS:7473-98-5
MF:C10H12O2
MW:164.2
EINECS:231-272-0
Product Categories:Other Products;Functional Materials;Photopolymerization Initiators;Acetophenone;Organic Photoinitiators;Polymerization Initiators;Industrial/Fine Chemicals;Additives for Plastic;Pharmaceutical Intermediates
Mol File:7473-98-5.mol
2-Hydroxy-2-methylpropiophenone Structure
2-Hydroxy-2-methylpropiophenone Chemical Properties
Melting point 4°C
Boiling point 102-103 °C4 mm Hg(lit.)
density 1.077 g/mL at 25 °C(lit.)
vapor pressure 0.57Pa at 20℃
refractive index n20/D 1.533(lit.)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Practically insoluble in water
form clear liquid
pka13.23±0.29(Predicted)
Specific Gravity1.077
color Colorless to Light orange to Yellow
Water Solubility 13.3g/L at 20℃
InChIKeyXMLYCEVDHLAQEL-UHFFFAOYSA-N
LogP1.62 at 25℃
CAS DataBase Reference7473-98-5(CAS DataBase Reference)
EPA Substance Registry System1-Propanone, 2-hydroxy-2-methyl-1-phenyl- (7473-98-5)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 23-36/37/39
RIDADR 3082
WGK Germany 3
RTECS UC2977245
HazardClass 9
PackingGroup III
HS Code 29144000
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Hydroxy-2-methylpropiophenone Usage And Synthesis
Uses

2-Hydroxy-2-methylpropiophenone is a photoinitiator.In addition, 2-hydroxy-2-methylpropiophenone is an important organic intermediate (building block) to synthetize substituted propiophenone products.

Chemical PropertiesYellowish clear liquid
Uses2-Hydroxy-2-benzoylpropane was used as a catalyst in real-time kinetic study of laser-induced polymerization. It is also a photoinitiator.
Synthesis Reference(s)Tetrahedron Letters, 29, p. 4365, 1988 DOI: 10.1016/S0040-4039(00)80496-7
General Description2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.
HazardModerately toxic by ingestion.
Flammability and ExplosibilityNotclassified
2-Hydroxy-2-methylpropiophenone Preparation Products And Raw materials
Raw materials1,2-Propanediol,2-methyl-1-phenyl--->2-chloro-2-methylpropiophenone-->Isobutyrophenone
eboracin 2-Hydroxy-2-methylpropiophenone 1,3-Indandione, 2-(3-tert-butyl-2-hydroxyphenyl)-2-hydroxy- 1-(4-ISOPROPYLPHENYL)-2-HYDROXY-2-METHYL-1-PROPANONE AURORA KA-5523 AURORA KA-4025 5'-BROMO-2'-HYDROXY-4'-METHYLPROPIOPHENONE 2'-HYDROXY-5'-METHYLPROPIOPHENONE 4-EPIANHYDROCHLORTETRACYCLINE HYDROCHLORIDE, CAN BE USED AS SECONDARY STANDARD Phenylacetone ANHYDROCHLORTETRACYCLINE HYDROCHLORIDE TIMTEC-BB SBB006499 2-(PHENYLEPOXY)TETRALONE AURORA KA-3185 LABOTEST-BB LT00244818 AURORA KA-3161 methylphenyl silicone resin CHLOROPHOSPHONAZO III
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