(3R)-8-hydroxy-3-methyl-isochroman-1-one

(3R)-8-hydroxy-3-methyl-isochroman-1-one Basic information
Product Name:(3R)-8-hydroxy-3-methyl-isochroman-1-one
Synonyms:(3R)-8-hydroxy-3-methyl-isochroman-1-one;(R)-3,4-Dihydro-3-methyl-8-hydroxyisocoumarin;(R)-3,4-Dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one;[R,(-)]-3,4-Dihydro-3α-methyl-8-hydroxyisocoumarin;(R)-(-)-Mellein, (S)-(+)-Mellein;(R)-()-Mellein;1H-2-Benzopyran-1-one, 3,4-dihydro-8-hydroxy-3-methyl-, (3R)-
CAS:480-33-1
MF:C10H10O3
MW:178.18
EINECS:200-258-5
Product Categories:
Mol File:480-33-1.mol
(3R)-8-hydroxy-3-methyl-isochroman-1-one Structure
(3R)-8-hydroxy-3-methyl-isochroman-1-one Chemical Properties
Melting point 58-58.5 °C
Boiling point 392.7±42.0 °C(Predicted)
density 1.252±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka9.86±0.40(Predicted)
form A crystalline solid
CAS DataBase Reference480-33-1
Safety Information
MSDS Information
(3R)-8-hydroxy-3-methyl-isochroman-1-one Usage And Synthesis
Uses(R)-(?)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(?)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 μM.[Cayman Chemical]
(3R)-8-hydroxy-3-methyl-isochroman-1-one Preparation Products And Raw materials
2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether beta-Sitosterol hydroxygenkwanin alpha-Terpineol beta-Eudesmol MOSLOFLAVONE alpha-Cyperone Isochroman

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