6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine

6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Basic information

Product Name:	6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine
Synonyms:	6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine;6-(1-BroMoethyl)-4-c;PyriMidine, 4-(1-broMoethyl)-6-chloro-5-fluoro-;4-chloro-5-fluoro-6-(1-bromoethyl)-pyrimidine;Voriconazole Impurity 4;-6-chloro-5-fluoropyrimidine;Voriconazole impurity 3 (bromide);synthesis-14-001
CAS:	188416-28-6
MF:	C6H5BrClFN2
MW:	239.47
EINECS:
Product Categories:	Fluorine series;pyrimidine
Mol File:	188416-28-6.mol

6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Chemical Properties

Boiling point	257.8±35.0 °C(Predicted)
density	1.725±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	-2.62±0.35(Predicted)

Safety Information

HS Code

2933599590

MSDS Information

6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Usage And Synthesis

Uses	4-(1-Bromoethyl)-6-chloro-5-fluoropyrimidine is used in preparation of Voriconazole intermediate.

6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine Preparation Products And Raw materials

Raw materials

4-Ethyl-5-fluoro-6-hydroxypyrimidine-->4-Chloro-6-ethyl-5-fluoropyrimidine-->Ethyl 2-fluoro-3-oxopentanoate-->2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE

rac 5-Desfluoro Voriconazole Voriconazole 4-Chloro-6-ethyl-5-fluoropyrimidine FENOFIBRIC ACID ETHYL ESTER ent-Voriconazole 4-Ethyl-5-fluoropyrimidine 4-Ethyl-5-fluoro-6-hydroxypyrimidine Voriconazole-d3 6-(1-Bromoethyl)-4-chloro-5-fluoropyrimidine 5-Fluoropyrimidine Fluorine Phenethyl chloride Difluorochloromethane Pyrimidine, 4-(bromomethyl)-2-chloro- (9CI) Fluorocytosine Pyrimidine, 4-chloro-5-fluoro- (9CI) 5-Fluorouracil DIETHYLALUMINUM CHLORIDE

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