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| | EMITEFUR Basic information |
| Product Name: | EMITEFUR | | Synonyms: | EMITEFUR;3-[[3-(Ethoxymethyl)-5-fluoro-3，6-dihydro-2，6-dioxo-1(2H)-pyrim-idinyl]carbonyl]benzoic acid 6-(benzoyloxy)- 3-cyano-2-pyridinyl ester;3-[[[3-(Ethoxymethyl)-5-fluoro-1,2,3,6-tetrahydro-2,6-dioxopyrimidin]-1-yl]carbonyl]benzoic acid 6-(benzoyloxy)-3-cyano-2-pyridinyl ester;3-[[3-(Ethoxymethyl)-5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-1-yl]carbonyl]benzoic acid 6-(benzoyloxy)-3-cyano-2-pyridyl ester;BOF-A2;BOF-A-2;Benzoic acid, 3-[[3-(ethoxymethyl)-5-fluoro-3,6-dihydro-2,6-dioxo-1(2H)-pyrimidinyl]carbonyl]-, 6-(benzoyloxy)-3-cyano-2-pyridinyl ester;EMITEFUR USP/EP/BP | | CAS: | 110690-43-2 | | MF: | C28H19FN4O8 | | MW: | 558.47 | | EINECS: | | | Product Categories: | | | Mol File: | 110690-43-2.mol |  |
| | EMITEFUR Chemical Properties |
| Melting point | 162-164° | | Boiling point | 755.1±70.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | -5.94±0.40(Predicted) | | CAS DataBase Reference | 110690-43-2 |
| Toxicity | LD50 in mice, male rats, female rats (mg/kg): >5000, 1850, 1934 orally (Kiroshita) |
| | EMITEFUR Usage And Synthesis |
| Uses | EMITEFUR is used for antineoplastic, it is used in the treatment of stomach, colorectal, breast, nonsmall cell lung, and pancreatic cancers (inhibits DNA synthesis and RNA function).
| | Hazard | A poison by ingestion. A reproductive
hazard.
| | Safety Profile | A poison by ingestion andsubcutaneous routes. Experimental reproductive effects.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx and F-. |
| | EMITEFUR Preparation Products And Raw materials |
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