Lisinopril R,S,S-Diketopiperazine

Lisinopril R,S,S-Diketopiperazine Basic information
Product Name:Lisinopril R,S,S-Diketopiperazine
Synonyms:(2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-phenylbutanoic Acid;Lisinopril R,S,S-Diketopiperazine;(2S)-2-[(3S,8aR)-3-(4-Aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-α]pyrazin-2(1H)-yl]-4-phenylbutanoic Acid;Pyrrolo[1,2-a]pyrazine-2(1H)-acetic acid, 3-(4-aMinobutyl)hexahydro-1,4-dioxo-a-(2-phenylethyl)-, (aS,3S,8aR)-;Lisinopril EP IMpurity D;Lisinopril Impurity 4(Lisinopril EP Impurity D);Lisinopril-EP-Imp-D;Lisinopril impurity 3/Lisinopril EP Impurity D/R,S,S-Diketopiperazine
CAS:219677-82-4
MF:C21H29N3O4
MW:387.47
EINECS:
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Various Metabolites and Impurities;Pharmaceuticals
Mol File:219677-82-4.mol
Lisinopril R,S,S-Diketopiperazine Structure
Lisinopril R,S,S-Diketopiperazine Chemical Properties
Melting point >214oC (dec.)
Boiling point 650.8±55.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka3.56±0.10(Predicted)
form Solid
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
Lisinopril R,S,S-Diketopiperazine Usage And Synthesis
UsesLisinopril impurity
UsesLisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).
DefinitionChEBI: Lisinopril (8r,s)-diketopiperazine is a dipeptide.
Lisinopril R,S,S-Diketopiperazine Preparation Products And Raw materials
Lisinopril Dihydrate Lisinopril S,S,S-Diketopiperazine p-Toluenesulfonic acid monohydrate DL-Homophenylalanine Lisinopril Cyclohexyl Analog Lisinopril EP Impurity E N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine Lisinopril R,S,S-Diketopiperazine (3-OXO-1-PIPERAZINYL)ACETIC ACID Lisinopril (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE Pyrrolo[1,2-a]pyrazine, octahydro-, (8aR)- (9CI)

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